Effects of synthetic A3 adenosine receptor agonists on cell proliferation and viability are receptor independent at micromolar concentrations

2012 ◽  
Vol 69 (3) ◽  
pp. 405-417 ◽  
Author(s):  
Petr Mlejnek ◽  
Petr Dolezel ◽  
Ivo Frydrych
Keyword(s):  
Cell Proliferation ◽  
Adenosine Receptor ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor

Design, synthesis and evaluation of N6-substituted 2-aminoadenosine-5′-N-methylcarboxamides as A3 adenosine receptor agonists

MedChemComm ◽  
2014 ◽  
Vol 5 (2) ◽  
pp. 192-196 ◽  
Author(s):  
Shane M. Devine ◽  
Lauren T. May ◽  
Peter J. Scammells
Keyword(s):  
Adenosine Receptor ◽  
Design Synthesis ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor

A series of N6-substituted 2-aminoadenosine-5′-N-methylcarboxamides were synthesized from the versatile intermediate, O6-(benzotriazol-1-yl)-2-amino-2′,3′-O-isopropylideneinosine-5′-N-methylcarboxamide (1) and evaluated as A3 adenosine receptor agonists.

N6-Ethyl-2-alkynyl NECAs, Selective Human A3 Adenosine Receptor Agonists.

ChemInform ◽  
2006 ◽  
Vol 37 (31) ◽  
Author(s):  
Ran Zhu ◽  
Cynthia R. Frazier ◽  
Joel Linden ◽  
Timothy L. Macdonald
Keyword(s):  
Adenosine Receptor ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor

scholarly journals Resistance of Muscle to Tumor Metastases: A Role for A3 Adenosine Receptor Agonists

Neoplasia ◽  
2001 ◽  
Vol 3 (2) ◽  
pp. 125-131 ◽  
Author(s):  
Sara Bar-Yehuda ◽  
Faina Barer ◽  
Lea Volisson ◽  
Pnina Fishman
Keyword(s):  
Adenosine Receptor ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor ◽  
Tumor Metastases

Synthesis and evaluation of new N6-substituted adenosine-5′-N-methylcarboxamides as A3 adenosine receptor agonists

2010 ◽  
Vol 18 (9) ◽  
pp. 3078-3087 ◽  
Author(s):  
Shane M. Devine ◽  
Alison Gregg ◽  
Heidi Figler ◽  
Kate McIntosh ◽  
Vijay Urmaliya ◽  
...  
Keyword(s):  
Adenosine Receptor ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor

N6-Ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists

2006 ◽  
Vol 16 (9) ◽  
pp. 2416-2418 ◽  
Author(s):  
Ran Zhu ◽  
Cynthia R. Frazier ◽  
Joel Linden ◽  
Timothy L. Macdonald
Keyword(s):  
Adenosine Receptor ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor
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