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A Phase I Study to Evaluate the Pharmacokinetics and Safety of Lorlatinib in Adults with Mild, Moderate, and Severe Renal Impairment
European Journal of Drug Metabolism and Pharmacokinetics
◽
10.1007/s13318-021-00747-4
◽
2022
◽
Author(s):
Swan Lin
◽
Jason Gong
◽
George C. Canas
◽
Peter Winkle
◽
Kathleen Pelletier
◽
...
Keyword(s):
Renal Impairment
◽
Phase I
◽
Phase I Study
◽
Severe Renal Impairment
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A Phase I Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Adults With Severe Renal Impairment and Healthy Matched Control Participants
Clinical Pharmacology in Drug Development
◽
10.1002/cpdd.664
◽
2019
◽
Vol 8
(5)
◽
pp. 674-681
◽
Cited By ~ 6
Author(s):
Ridhi Parasrampuria
◽
Susan L. Ford
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Yu Lou
◽
Caifeng Fu
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Kalpana K. Bakshi
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...
Keyword(s):
Renal Impairment
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Phase I
◽
Phase I Study
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Matched Control
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Severe Renal Impairment
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A Phase I Study in Patients with Solid or Hematologic Malignancies of the Dose Proportionality of Subcutaneous Azacitidine and Its Pharmacokinetics in Patients with Severe Renal Impairment
Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
◽
10.1002/phar.1371
◽
2013
◽
Vol 34
(5)
◽
pp. 440-451
◽
Cited By ~ 7
Author(s):
Eric Laille
◽
Sanjay Goel
◽
Alain C. Mita
◽
Nashat Y. Gabrail
◽
Kevin Kelly
◽
...
Keyword(s):
Renal Impairment
◽
Phase I
◽
Phase I Study
◽
Severe Renal Impairment
◽
Hematologic Malignancies
◽
Dose Proportionality
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A Phase I, Open-Label, Parallel-Group, Single-Dose Trial of the Pharmacokinetics, Safety, and Tolerability of Cannabidiol in Subjects with Mild to Severe Renal Impairment
Clinical Pharmacokinetics
◽
10.1007/s40262-019-00841-6
◽
2019
◽
Vol 59
(6)
◽
pp. 747-755
◽
Cited By ~ 8
Author(s):
Bola Tayo
◽
Lesley Taylor
◽
Farhad Sahebkar
◽
Gilmour Morrison
Keyword(s):
Single Dose
◽
Renal Impairment
◽
Phase I
◽
Severe Renal Impairment
◽
Open Label
◽
Parallel Group
◽
Dose Trial
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The effect of varying degrees of renal impairment on the single dose pharmacokinetic profile of orally administered lurasidone: a phase I study
http://isrctn.org/>
◽
10.1186/isrctn16720571
◽
2012
◽
Author(s):
Shelda Alcock
Keyword(s):
Single Dose
◽
Renal Impairment
◽
Phase I
◽
Phase I Study
◽
Pharmacokinetic Profile
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Effect of renal impairment on the pharmacokinetics of prucalopride: a single- dose open-label Phase I study
Drug Design Development and Therapy
◽
10.2147/dddt.s36142
◽
2012
◽
pp. 407
Author(s):
Lieve Vandeplassche
◽
Smith
◽
Mannaert
◽
Verhaeghe
◽
Kerstens
◽
...
Keyword(s):
Single Dose
◽
Renal Impairment
◽
Phase I
◽
Phase I Study
◽
Open Label
◽
Open Label Phase
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How to manage intravenous vinflunine in cancer patients with renal impairment: results of a pharmacokinetic and tolerability phase I study
British Journal of Clinical Pharmacology
◽
10.1111/bcp.12218
◽
2014
◽
Vol 77
(3)
◽
pp. 498-508
◽
Cited By ~ 8
Author(s):
Nicolas Isambert
◽
Jean Pierre Delord
◽
Jean Marc Tourani
◽
Pierre Fumoleau
◽
Alain Ravaud
◽
...
Keyword(s):
Renal Impairment
◽
Phase I
◽
Cancer Patients
◽
Phase I Study
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A multicenter, phase I, pharmacokinetic study of osimertinib in cancer patients with normal renal function or severe renal impairment
Pharmacology Research & Perspectives
◽
10.1002/prp2.613
◽
2020
◽
Vol 8
(4)
◽
Author(s):
Karthick Vishwanathan
◽
Inmaculada Sanchez‐Simon
◽
Bhumsuk Keam
◽
Nicolas Penel
◽
Maria Miguel‐Luken
◽
...
Keyword(s):
Renal Function
◽
Renal Impairment
◽
Phase I
◽
Cancer Patients
◽
Pharmacokinetic Study
◽
Normal Renal Function
◽
Severe Renal Impairment
◽
Multicenter Phase
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Phase I study of the effects of renal impairment on the pharmacokinetics and safety of satraplatin in patients with refractory solid tumors
Annals of Oncology
◽
10.1093/annonc/mdr358
◽
2012
◽
Vol 23
(4)
◽
pp. 1037-1044
◽
Cited By ~ 8
Author(s):
M.D. Galsky
◽
L.H. Camacho
◽
E.G. Chiorean
◽
D. Mulkerin
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D.S. Hong
◽
...
Keyword(s):
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Phase I
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Solid Tumors
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Phase I Study
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Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations
Yearbook of Oncology
◽
10.1016/s1040-1741(08)70507-4
◽
2007
◽
Vol 2007
◽
pp. 342-343
Author(s):
M.S. Gordon
Keyword(s):
Malignant Melanoma
◽
Phase I
◽
Phase I Study
◽
Advanced Malignant Melanoma
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Toxicity reduction of adenovirus mediated thymidine kinase gene therapy for ovarian cancer and subsequent combination with topoisomerase inhibitors: Design of a clinical phase I study
Journal of the Society for Gynecologic Investigation
◽
10.1016/s1071-5576(97)86111-4
◽
1998
◽
Vol 5
(1)
◽
pp. 47A-47A
◽
Cited By ~ 1
Author(s):
X TONG
◽
D ENGEHAUSEN
◽
D SHINE
◽
I AGOULNIK
◽
T KIM
◽
...
Keyword(s):
Ovarian Cancer
◽
Gene Therapy
◽
Phase I
◽
Thymidine Kinase
◽
Phase I Study
◽
Thymidine Kinase Gene
◽
Topoisomerase Inhibitors
◽
Kinase Gene
◽
Clinical Phase
◽
Toxicity Reduction
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