Unstable angina pectoris: National cooperative study group to compare medical and surgical therapy

1981 ◽  
Vol 48 (3) ◽  
pp. 517-524 ◽  
Author(s):  
Richard O. Russell ◽  
Roger E. Moraski ◽  
Nicholas T. Kouchoukos ◽  
Robert B. Karp ◽  
John A. Mantle ◽  
...  
1982 ◽  
Vol 34 (4) ◽  
pp. 427-434 ◽  
Author(s):  
Ellis L. Jones ◽  
Thadeus F. Waites ◽  
Joe M. Craver ◽  
David K. Bone ◽  
Charles R. Hatcher ◽  
...  

Circulation ◽  
1994 ◽  
Vol 89 (2) ◽  
pp. 596-603 ◽  
Author(s):  
M L Simoons ◽  
M J de Boer ◽  
M J van den Brand ◽  
A J van Miltenburg ◽  
J C Hoorntje ◽  
...  

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
M. B. I. Lobbes ◽  
M. E. Kooi ◽  
E. Lutgens ◽  
A. W. Ruiters ◽  
V. Lima Passos ◽  
...  

We evaluated leukocyte counts and levels of CRP, fibrinogen, MPO, and PAPP-A in patients with stable and unstable angina pectoris, acute myocardial infarction, and healthy controls. All biomarkers were analyzed again after 6 months. Leukocyte counts and concentrations of fibrinogen, CRP, MPO, and PAPP-A were significantly increased in patients with acute myocardial infarction. Leukocyte counts and concentrations of MPO were significantly increased in patients with unstable angina pectoris compared with controls. After 6 months, leukocyte counts and MPO concentrations were still increased in patients with acute myocardial infarction when compared to controls. Discriminant analysis showed that leukocyte counts, MPO, and PAPP-A concentrations classified study group designation for acute coronary events correctly in 83% of the cases. In conclusion, combined assessment of leukocyte counts, MPO, and PAPP-A was able to correctly classify acute coronary events, suggesting that this could be a promising panel for a multibiomarker approach to assess cardiovascular risk.


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