7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes

Hiroshi Yamazaki; Kiyoshi Inoue; Mayumi Mimura; Yoshimitsu Oda; F.Peter Guengerich; Tsutomu Shimada

doi:10.1016/0006-2952(95)02178-7

7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes

Biochemical Pharmacology ◽

10.1016/0006-2952(95)02178-7 ◽

1996 ◽

Vol 51 (3) ◽

pp. 313-319 ◽

Cited By ~ 71

Author(s):

Hiroshi Yamazaki ◽

Kiyoshi Inoue ◽

Mayumi Mimura ◽

Yoshimitsu Oda ◽

F.Peter Guengerich ◽

...

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes

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Interindividual variation in the isomerization of 4- hydroxytamoxifen by human liver microsomes: involvement of cytochromes P450

Carcinogenesis ◽

10.1093/carcin/15.12.2733 ◽

1994 ◽

Vol 15 (12) ◽

pp. 2733-2738 ◽

Cited By ~ 29

Author(s):

M.L. Williams ◽

M. S. Lennard ◽

I. J. Martin ◽

G. T. Tucker

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Interindividual Variation

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IN VITRO METABOLISM OF THE CALMODULIN ANTAGONIST DY-9760e (3-[2-[4-(3-CHLORO-2-METHYLPHENYL)-1-PIPERAZINYL]ETHYL]-5,6-DIMETHOXY-1-(4-IMIDAZOLYLMETHYL)-1H-INDAZOLE DIHYDROCHLORIDE 3.5 HYDRATE) BY HUMAN LIVER MICROSOMES: INVOLVEMENT OF CYTOCHROMES P450 IN ATYPICAL KINETICS AND POTENTIAL DRUG INTERACTIONS

Drug Metabolism and Disposition ◽

10.1124/dmd.105.004903 ◽

2005 ◽

Vol 33 (11) ◽

pp. 1628-1636 ◽

Cited By ~ 5

Author(s):

Shuko Tachibana ◽

Yuko Fujimaki ◽

Hiroyuki Yokoyama ◽

Osamu Okazaki ◽

Ken-ichi Sudo

Keyword(s):

Drug Interactions ◽

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

In Vitro Metabolism ◽

Potential Drug ◽

Calmodulin Antagonist

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Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.374 ◽

2003 ◽

Vol 24 (9) ◽

pp. 375-384 ◽

Cited By ~ 51

Author(s):

Anima Ghosal ◽

Neil Hapangama ◽

Yuan Yuan ◽

Xiaowen Lu ◽

Debra Horne ◽

...

Keyword(s):

Enzyme Activities ◽

Human Liver ◽

Rapid Determination ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes

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Human Liver Microsomes Are Efficient Catalysts of 1,3-Butadiene Oxidation: Evidence for Major Roles by Cytochromes P450 2A6 and 2E1

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1994.1246 ◽

1994 ◽

Vol 311 (2) ◽

pp. 342-349 ◽

Cited By ~ 101

Author(s):

R.J. Duescher ◽

A.A. Elfarra

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes

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Metabolism of Anethole Dithiolethione by Rat and Human Liver Microsomes: Formation of Various Products Deriving from Its O-Demethylation and S-Oxidation. Involvement of Cytochromes P450 and Flavin Monooxygenases in These Pathways

Drug Metabolism and Disposition ◽

10.1124/dmd.118.082545 ◽

2018 ◽

Vol 46 (10) ◽

pp. 1390-1395 ◽

Cited By ~ 6

Author(s):

Martin Dulac ◽

Amor Sassi ◽

Citra Nagarathinan ◽

Marie-Odile Christen ◽

Patrick M. Dansette ◽

...

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

S Oxidation

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Different substrate elimination rates of model drugs pH-dependently mediated by flavin-containing monooxygenases and cytochromes P450 in human liver microsomes

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2021.100412 ◽

2021 ◽

pp. 100412

Author(s):

Tomomi Taniguchi-Takizawa ◽

Nozomu Kato ◽

Makiko Shimizu ◽

Toshiyuki Kume ◽

Hiroshi Yamazaki

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes

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Roles of Cytochromes P450 1A2 and 3A4 in the Oxidation of Estradiol and Estrone in Human Liver Microsomes

Chemical Research in Toxicology ◽

10.1021/tx970217f ◽

1998 ◽

Vol 11 (6) ◽

pp. 659-665 ◽

Cited By ~ 119

Author(s):

Hiroshi Yamazaki ◽

Peter M. Shaw ◽

F. Peter Guengerich ◽

Tsutomu Shimada

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes

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The Metabolism of Pyrazoloacridine (NSC 366140) by Cytochromes P450 and Flavin Monooxygenase in Human Liver Microsomes

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-0557-03 ◽

2004 ◽

Vol 10 (4) ◽

pp. 1471-1480 ◽

Cited By ~ 21

Author(s):

Joel M. Reid ◽

Denise L. Walker ◽

Jennifer K. Miller ◽

Linda M. Benson ◽

Andrew J. Tomlinson ◽

...

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Flavin Monooxygenase

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Inhibitory Effects of 12 Ginsenosides on the Activities of Seven Cytochromes P450 in Human Liver Microsomes

Mass Spectrometry Letters ◽

10.5478/msl.2016.7.4.106 ◽

2016 ◽

Vol 7 (4) ◽

pp. 106-110 ◽

Cited By ~ 1

Author(s):

Jung Jae Jo ◽

Riya Shrestha ◽

Sangkyu Lee

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Inhibitory Effects

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Metabolism of Methyl tert-butyl Ether and Other Gasoline Ethers by Human Liver Microsomes and Heterologously Expressed Human Cytochromes P450: Identification of CYP2A6 as a Major Catalyst

Toxicology and Applied Pharmacology ◽

10.1006/taap.1999.8750 ◽

1999 ◽

Vol 160 (1) ◽

pp. 43-48 ◽

Cited By ~ 31

Author(s):

Jun-Yan Hong ◽

Yong-Yu Wang ◽

Flordeliza Y. Bondoc ◽

Maojung Lee ◽

Chung S. Yang ◽

...

Keyword(s):

Human Liver ◽

Cytochromes P450 ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Methyl Tert Butyl Ether ◽

Butyl Ether ◽

Tert Butyl

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