Alterations of corticotropin-releasing factor-like immunoreactivity in different brain regions after acute cocaine administration in rats

1993 ◽  
Vol 616 (1-2) ◽  
pp. 315-319 ◽  
Author(s):  
Zoltán Sarnyai ◽  
Éva Bíró ◽  
János Gardi ◽  
Miklós Vecsernyés ◽  
János Julesz ◽  
...  
Keyword(s):  
Brain Regions ◽  
Corticotropin Releasing Factor ◽  
Cocaine Administration

Repeated cocaine administration does not affect 5-HT receptor subtypes (5-HT1A, 5-HT2) in several rat brain regions

1993 ◽  
Vol 238 (2-3) ◽  
pp. 425-429 ◽  
Author(s):  
Javaid I. Javaid ◽  
Sanjeev K. Sahni ◽  
Subhash C. Pandey ◽  
John M. Davis
Keyword(s):  
Rat Brain ◽  
Brain Regions ◽  
Receptor Subtypes ◽  
Cocaine Administration ◽  
Rat Brain Regions

The Role of the Glutamatergic System in Posttraumatic Stress Disorder

CNS Spectrums ◽  
2008 ◽  
Vol 13 (7) ◽  
pp. 585-591 ◽  
Author(s):  
Jyotsna Nair ◽  
Sarbjot Singh Ajit
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Anxiety Disorders ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Brain Regions ◽  
Corticotropin Releasing Factor ◽  
Glutamatergic System ◽  
Symptom Complex ◽  
Crf System

ABSTRACTAntiglutamatergic agents, such as lamotrigine, have been used successfully for the treatment of posttraumatic stress disorder (PTSD). They could be potentially acting through the stabilization of the corticotropin-releasing factor (CRF) systems. Glutamate mediates CRF release in various brain regions involved in the pathophysiology of PTSD, antiglutamatergic agents could stabilize the CRF system and, thereby, improve the symptom complex of PTSD (reexperiencing, hyperarousal, and avoidance). The role of glutamate and CRF in PTSD and other anxiety disorders are still being elucidated. However, it is clear that the glutamatergic systems play a role in the pathophysiology of PTSD.

Repeated crack cocaine administration alters panic-related responses and delta FosB immunoreactivity in panic-modulating brain regions

2021 ◽  
Vol 239 (4) ◽  
pp. 1179-1191
Author(s):  
Barbara dos Anjos Rosário ◽  
Maria de Fátima Santana de Nazaré ◽  
Jéssica Alves Lemes ◽  
José Simões de Andrade ◽  
Regina Barbosa da Silva ◽  
...  
Keyword(s):  
Crack Cocaine ◽  
Brain Regions ◽  
Cocaine Administration ◽  
Delta Fosb
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