An approach to branched-chain amino sugars, particularly derivatives of l-vancosamine (3-amino-2,3,6-trideoxy-3-C-methyl-l-lyxo-hexose) and its d enantiomer, via the cyanohydrin route

1982 ◽  
Vol 110 (2) ◽  
pp. 207-215 ◽  
Author(s):  
John S. Brimacombe ◽  
Annalee S. Mengech ◽  
Khandker M.M. Rahman ◽  
Leslie C.N. Tucker
Keyword(s):  
Amino Sugars ◽  
Branched Chain ◽  
Derivatives Of

Amino sugars. XXVII. The synthesis of derivatives of 3-amino-3,4,6-trideoxy-D- or L-xylo-hexopyranose

1972 ◽  
Vol 37 (9) ◽  
pp. 2985-2993 ◽  
Author(s):  
K. Kefurt ◽  
K. Čapek ◽  
J. Čapková ◽  
Z. Kefurtová ◽  
J. Jarý
Keyword(s):  
Amino Sugars ◽  
Derivatives Of

Synthesis and Structural Analysis of Branched-Chain Derivatives of Methyl Oleate

2008 ◽  
Vol 85 (7) ◽  
pp. 647-653 ◽  
Author(s):  
Oliver D. Dailey ◽  
Nicolette T. Prevost ◽  
Gary D. Strahan
Keyword(s):  
Structural Analysis ◽  
Methyl Oleate ◽  
Branched Chain ◽  
Derivatives Of

scholarly journals Amino-sugars enhance recognition and phagocytosis of particles by human neutrophils

Blood ◽  
1983 ◽  
Vol 62 (3) ◽  
pp. 697-701 ◽  
Author(s):  
RL Doolittle ◽  
CH Packman ◽  
MA Lichtman
Keyword(s):  
Human Neutrophils ◽  
Amino Sugars ◽  
Carbohydrate Binding ◽  
Carbohydrate Recognition ◽  
Membrane Structures ◽  
Fluorescent Beads ◽  
Amino Derivatives ◽  
Recognition Systems ◽  
Dose Dependent ◽  
Derivatives Of

Abstract Neutrophils were examined for their ability to recognize and ingest beads coated with amino-derivatives of glucose, mannose, and galactose. Radioactive or fluorescent beads coated with any of the three sugars were ingested to an extent three times that observed with albumin- coated beads. Enhancement of ingestion of sugar-coated beads was much more evident when examined by electron micrographic studies. Inclusion of glucose or mannose in the medium with glucose- or mannose-coated beads caused a dose-dependent reduction of ingestion to control levels, but ingestion of galactose-coated beads was poorly inhibited. Similarly, galactose or fucose (6-deoxy-galactose) markedly inhibited ingestion of galactose-coated beads, but caused only a slight decrease in ingestion of glucose- or mannose-coated beads. Thus, neutrophils possess carbohydrate-binding membrane structures that can mediate recognition and ingestion of sugar-coated beads. Such carbohydrate recognition systems may underlie certain interactions of neutrophils and other surfaces.

The synthesis of branched-chain amino sugars from C-methylene sugars: a re-assignment of structure

1975 ◽  
Vol 44 (2) ◽  
pp. C9-C11 ◽  
Author(s):  
John S. Brimacombe ◽  
J. Allen Miller ◽  
U. Zakir
Keyword(s):  
Amino Sugars ◽  
Branched Chain
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