Short latency somatosensory evoked potentials and brain-stem auditory evoked potentials in coma due to CNS depressant drug poisoning. Preliminary observations

1988 ◽  
Vol 70 (6) ◽  
pp. 482-489 ◽  
Author(s):  
E. Rumpl ◽  
M. Prugger ◽  
H.J. Battista ◽  
F. Badry ◽  
F. Gerstenbrand ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Brain Stem ◽  
Somatosensory Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Short Latency ◽  
Drug Poisoning ◽  
Cns Depressant ◽  
Depressant Drug

Short-latency Somatosensory Evoked Potentials in Patients with Brain Stem Tumor: Study of N20 and N18 Potentials

1997 ◽  
Vol 37 (7) ◽  
pp. 525-532 ◽  
Author(s):  
Masafumi FUKUDA ◽  
Shigeki KAMEYAMA ◽  
Yoshiho HONDA ◽  
Hidetoshi YAMAZAKI ◽  
Tadashi KAWAGUCHI ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Brain Stem ◽  
Somatosensory Evoked Potentials ◽  
Short Latency ◽  
Brain Stem Tumor ◽  
Tumor Study

Electrophysiological Detection of the Neurotoxic Effects of Acrylamide and 2,5-Hexanedione on the Rat Sensory System

2000 ◽  
Vol 19 (3) ◽  
pp. 187-193 ◽  
Author(s):  
Todd L. Towell ◽  
Linda Shell ◽  
Karen Dyer Inzana ◽  
Bernard S. Jortner ◽  
Marion Ehrich
Keyword(s):  
Nervous System ◽  
Evoked Potentials ◽  
Brain Stem ◽  
Somatosensory Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Sensory System ◽  
Intraperitoneal Route ◽  
Neurotoxic Effects ◽  
Ad Libitum ◽  
Sensory Nervous System

Brain stem auditory evoked potentials (BAEP) and somatosensory evoked potentials (SEP), recorded from subcutaneously placed electrodes in anesthetized rats, were used to detect neurotoxic effects of acrylamide and 2,5-hexanedione on the sensory nervous system. Both neurotoxicants were administered for 21 days by the intraperitoneal route, using dosages of 20 mg/kg/day for acrylamide and 350 mg/kg/day for 2,5-hexanedione. Recordings were made before and 1, 2, and 3 weeks after dosing was initiated. Both food-restricted and ad libitum-fed rats served as controls. Results demonstrated that SEP waveforms generated in rats were sufficiently variable that differences among the groups were not detected. However, BAEP latencies were longer than those seen in control rats after 3 weeks of acrylamide treatment and after both 2 and 3 weeks of 2,5-hexanedione treatment. The effects of 2,5-hexanedione were more pronounced than those of acrylamide, and increased with length of the dosing period.

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