scholarly journals Detection of intercalation-induced changes in DNA structure by reaction with diethyl pyrocarbonate or potassium permanganate Evidence against the induction of Hoogsteen base pairing by echinomycin

FEBS Letters ◽  
1988 ◽  
Vol 231 (1) ◽  
pp. 172-176 ◽  
Author(s):  
Claus Jeppesen ◽  
Peter E. Nielsen
Keyword(s):  
Potassium Permanganate ◽  
Dna Structure ◽  
Base Pairing ◽  
Diethyl Pyrocarbonate ◽  
Hoogsteen Base Pairing ◽  
Induced Changes

scholarly journals Footprinting studies on the effect of echinomycin on the structure of a bent DNA fragment

1990 ◽  
Vol 269 (1) ◽  
pp. 217-221 ◽  
Author(s):  
K R Fox ◽  
E Kentebe
Keyword(s):  
Binding Sites ◽  
Dna Structure ◽  
Drug Binding ◽  
Micrococcal Nuclease ◽  
Kinetoplast Dna ◽  
Bent Dna ◽  
Diethyl Pyrocarbonate ◽  
Drug Binding Sites ◽  
Dna Fragment

The interaction of echinomycin with a kinetoplast DNA fragment which contains phased runs of adenine residues has been examined by various footprinting techniques. DNAase I footprinting confirms that all drug-binding sites contain the dinucleotide CpG. However, not all such sequences are protected. Three sites, each of which is located between two adenine tracks in the sequence GCGA, are not protected from DNAase I attack. Enhanced cleavage by DNAase I, DNAase II and micrococcal nuclease is observed in regions surrounding drug-binding sites. The results suggest that echinomycin alters the conformation of the AT tracks, making them more like an average DNA structure. Echinomycin renders adenine residues in the sequence CGA hyper-reactive to diethyl pyrocarbonate.

Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing

Nature ◽  
2004 ◽  
Vol 430 (6997) ◽  
pp. 377-380 ◽  
Author(s):  
Deepak T. Nair ◽  
Robert E. Johnson ◽  
Satya Prakash ◽  
Louise Prakash ◽  
Aneel K. Aggarwal
Keyword(s):  
Dna Polymerase ◽  
Base Pairing ◽  
Human Dna ◽  
Hoogsteen Base Pairing ◽  
Dna Polymerase Ι

scholarly journals Structure of the 1,N2-Ethenodeoxyguanosine Adduct Opposite Cytosine in Duplex DNA: Hoogsteen Base Pairing at pH 5.2†

2008 ◽  
Vol 21 (9) ◽  
pp. 1795-1805 ◽  
Author(s):  
Ganesh Shanmugam ◽  
Ivan D. Kozekov ◽  
F. Peter Guengerich ◽  
Carmelo J. Rizzo ◽  
Michael P. Stone
Keyword(s):  
Duplex Dna ◽  
Base Pairing ◽  
Hoogsteen Base Pairing

Environment induced changes in DNA structure

1986 ◽  
Vol 1 (1) ◽  
pp. 51-65 ◽  
Author(s):  
Walter A. Baase ◽  
John A. Schellman
Keyword(s):  
Dna Structure ◽  
Induced Changes

Parallel-stranded DNA with Hoogsteen base pairing stabilized by a trans-[Pt(NH3)2]2+ cross-link: characterization and conversion into a homodimer and a triplex

2000 ◽  
Vol 5 (5) ◽  
pp. 603-611 ◽  
Author(s):  
Jens Müller ◽  
Markus Drumm ◽  
Marc Boudvillain ◽  
Marc Leng ◽  
Einar Sletten ◽  
...  
Keyword(s):  
Base Pairing ◽  
Cross Link ◽  
Hoogsteen Base Pairing
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