Female sex steroid residues in the tissues of steers treated with progesterone and oestradiol-17β

1992 ◽  
Vol 52 (1) ◽  
pp. 105-109 ◽  
Author(s):  
T. Tsujioka ◽  
S. Ito ◽  
A. Ohga
Keyword(s):  
Author(s):  
S. Karkare ◽  
J. Gilloteaux ◽  
T. R. Kelly

Approximately 1 million people in the United States alone develop gallstones each year. The incidence is higher in women than in men and the ratio being 4 ≥ 1. A correlation has also been suggested between oral contraceptives and cholelithiasis. In addition, postmenopausal or cancer estrogen therapy has been reported to be a factor responsible for gallstone formation. Female sex hormone receptors have been detected not only in the gallbladder musculature, but also in its epithelium. As a follow up to experiments effectuated in the male and the ovariectomized Syrian hamster, this report shows that, a combination of a low cholesterol diet with female sex steroid treatment contributes to the formation of gallstone-like deposits, while modifying the surface epithelium morphology. Syrian hamsters (F1B strain, BioBreeders, Watertown MA) were housed under 12h light: 12 h dark cycle, at 20 °C, fed Purina chow and water ad libitum. Several duration/treatment groups were studied, but this report will focus on data obtained with the group injected weekly with estradiol valerate (E weekly, s.c. 8-10 μg/100 g.b.w., in corn oil) and with i.m. medroxyprogesterone acetate (DepoProvera Upjohn Co., Kalamazoo, MI; 8-10 mg/100 g.b.w.) for a 3-month period. Other parameters (blood and bile) were also studied but not reported here.


2004 ◽  
Vol 26 (2-4) ◽  
pp. 245-254 ◽  
Author(s):  
Mireya Marin-Husstege ◽  
Michela Muggironi ◽  
David Raban ◽  
Robert P. Skoff ◽  
Patrizia Casaccia-Bonnefil

2000 ◽  
Vol 62 (4) ◽  
pp. 1033-1039 ◽  
Author(s):  
P.R.R. Gangula ◽  
P. Lanlua ◽  
S. Wimalawansa ◽  
S. Supowit ◽  
D. DiPette ◽  
...  

2008 ◽  
Vol 60 (1) ◽  
pp. 86-86 ◽  
Author(s):  
SE Segerer ◽  
N Müller ◽  
J Van Den Brandt ◽  
M Kapp ◽  
J Dietl ◽  
...  

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