Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis

1988 ◽  
Vol 81 (4) ◽  
pp. 725-730 ◽  
Author(s):  
W. Skassa-Brociek ◽  
J. Bousquet ◽  
F. Montes ◽  
M. Verdier ◽  
D. Schwab ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Seasonal Allergic Rhinitis ◽  
Symptomatic Treatment ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Loratadine/Pseudoephedrine for Nasal Symptoms in Seasonal Allergic Rhinitis: A Double-Blind, Placebo-Controlled Study

2000 ◽  
Vol 79 (4) ◽  
pp. 254-267 ◽  
Author(s):  
Edith A. McFadden ◽  
Anil Gungor ◽  
Bernard Ng ◽  
Bülent Mamikoglu ◽  
Rizwan Moinuddin ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Seasonal Allergic Rhinitis ◽  
Fixed Combination ◽  
Nasal Congestion ◽  
Inferior Turbinate ◽  
Controlled Study ◽  
Life Questionnaire ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Nasal Symptoms

In this double-blind, placebo-controlled, crossover, parallel study, we treated 20 adults who had seasonal allergic rhinitis with once-daily fixed-combination loratadine/pseudoephedrine sulfate to observe its effect on relieving symptoms, primarily nasal congestion. Acoustic rhinometry detected a trend toward improvement in nasal patency, although the difference between pre- and post-treatment measures was not statistically significant. Endoscopic inferior turbinate photography documented that treatment led to statistically significant reductions in the amount of nasal edema and nasal secretions. The results of a quality-of-life questionnaire suggested that treatment alleviated nasal and ocular symptoms of rhinoconjunctivitis. An analysis of subjective visual analog scale scores showed a trend toward improvement in most but not all nasal symptoms. We conclude that once-a-day fixed-combination loratadine/pseudoephedrine is effective in relieving nasal congestion in patients with seasonal allergic rhinitis.

A randomized, double-blind placebo-controlled study of intranasal standardized cinnamon bark extract for seasonal allergic rhinitis

2019 ◽  
Vol 47 ◽  
pp. 102198
Author(s):  
Eleanor Steels ◽  
Elizabeth Steels ◽  
Pallavi Deshpande ◽  
Prasad Thakurdesai ◽  
Satish Dighe ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Seasonal Allergic Rhinitis ◽  
Controlled Study ◽  
Bark Extract ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Cinnamon Bark
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