Bioluminescent assay for human lymphocyte blast transformation

1995 ◽  
Vol 46 (1-2) ◽  
pp. 153-155 ◽  
Author(s):  
E.G. Bulanova ◽  
V.M. Budagyan ◽  
N.A. Romanova ◽  
L.Yu. Brovko ◽  
N.N. Ugarova
1968 ◽  
Vol 39 (5) ◽  
pp. 270-275 ◽  
Author(s):  
C. Bachi ◽  
A.M. Bussi ◽  
S. Sartoris ◽  
F. Vergnano ◽  
M. Fazio

1983 ◽  
Vol 5 (3) ◽  
pp. 249-256 ◽  
Author(s):  
M.V. LONDNER ◽  
S. FRANKENBURG ◽  
G.M. SLUTZKY ◽  
C.L. GREENBLATT

Molecules ◽  
2020 ◽  
Vol 25 (16) ◽  
pp. 3721 ◽  
Author(s):  
Tetiana Ilina ◽  
Weronika Skowrońska ◽  
Natalia Kashpur ◽  
Sebastian Granica ◽  
Agnieszka Bazylko ◽  
...  

Extracts from aerial parts of G. aparine (cleavers) constitute a herbal remedy with monography in British Herbal Pharmacopeia. On the European market, there are several drugs and food supplements consisting of Galium extracts. In folk medicine, cleavers was used topically in Europe, Asia, and the Americas to treat skin diseases. In several remedies, cleavers is also listed as an immunomodulatory active herb influencing the defense response of the human body. The aim of this study was to investigate the immunostimulatory activity and antioxidant potential in vitro of a raw infusion of cleavers and bioactive fractions. The functional activity of lymphocytes in the reaction of the lymphocyte blast transformation (RLBT) method was used for immunomodulatory activity assays and direct scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide (NO), and hydrogen peroxide (H2O2) was chosen for the examination of antioxidant activity. It was shown that both the raw extract and fractions show significant immunostimulatory and scavenging activities. The obtained data partially justify the traditional use of cleavers as topical remedy for skin infections and for wounds.


1970 ◽  
Vol 1 (6) ◽  
pp. 583-595 ◽  
Author(s):  
John W. Hadden ◽  
Elba M. Hadden ◽  
Elliott Middleton

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