Comparison of the effects of adjuvants and adjuvant doses on the quantitative and qualitative antibody response to selected antigens in New World squirrel monkeys Saimiri sciureus

Vaccine ◽  
1993 ◽  
Vol 11 (7) ◽  
pp. 730-736 ◽  
Author(s):  
Ronald Perraut ◽  
Erika Hundt ◽  
Olivier Garraud ◽  
Burkhard Enders ◽  
Jürg Gysin
1968 ◽  
Vol 5 (6) ◽  
pp. 538-560 ◽  
Author(s):  
G. E. McKissick ◽  
H. L. Ratcliffe ◽  
A. Koestner

An enzootic of toxoplasmosis occurred in caged squirrel monkeys ( Saimiri sciureus, a New World primate) which resulted in 9 deaths during an interval of 22 months. Diagnosis was based on morphology of the organism, character and distribution of the lesions, and laboratory history of the monkeys. The character of the lesions was essentially necrotic. The chronological incidence of the disease and distribution of lesions and organisms are tabulated. Trypanosoma cruzi which causes Chaga's disease is differentiated morphologically from toxoplasma. Incidence and lesions of the enzootic suggest 5 factors to be considered in the pathogenesis of toxoplasmosis in squirrel monkeys. They are: (1) lack of protective immunity, (2) local concentration of toxin and/or catabolites of reproduction of the organism, (3) individual tissue susceptibility to the organism, (4) capillary thrombosis, and (5) ability of the individual to adapt to its environment.


2013 ◽  
Vol 9 (6) ◽  
pp. 20130852 ◽  
Author(s):  
Andrea Ravignani ◽  
Ruth-Sophie Sonnweber ◽  
Nina Stobbe ◽  
W. Tecumseh Fitch

Sensitivity to dependencies (correspondences between distant items) in sensory stimuli plays a crucial role in human music and language. Here, we show that squirrel monkeys ( Saimiri sciureus ) can detect abstract, non-adjacent dependencies in auditory stimuli. Monkeys discriminated between tone sequences containing a dependency and those lacking it, and generalized to previously unheard pitch classes and novel dependency distances. This constitutes the first pattern learning study where artificial stimuli were designed with the species' communication system in mind. These results suggest that the ability to recognize dependencies represents a capability that had already evolved in humans’ last common ancestor with squirrel monkeys, and perhaps before.


Sign in / Sign up

Export Citation Format

Share Document