Opposite influences of dopaminergic pathways to the prefrontal cortex or the septum on the dopaminergic transmission in the nucleus accumbens. An in vivo voltammetric study

Neuroscience ◽  
1989 ◽  
Vol 29 (1) ◽  
pp. 45-56 ◽  
Author(s):  
A. Louilot ◽  
M. Le Moal ◽  
H. Simon
Keyword(s):  
Prefrontal Cortex ◽  
Nucleus Accumbens ◽  
Dopaminergic Transmission ◽  
Voltammetric Study ◽  
Dopaminergic Pathways

Alterations In Glutamate Synapses In The Nucleus Accumbens Following Sensitization To Cocaine

1999 ◽  
Vol 5 (S2) ◽  
pp. 1232-1233
Author(s):  
L. B. Kozell ◽  
C. K. Meshul
Keyword(s):  
Prefrontal Cortex ◽  
Locomotor Activity ◽  
Nucleus Accumbens ◽  
Behavioral Sensitization ◽  
Neural Mechanism ◽  
Cocaine Administration ◽  
Collaborative Studies ◽  
Abundant Evidence ◽  
Dopaminergic Pathways ◽  
Intermittent Cocaine

Repeated intermittent administration of cocaine to rodents has been shown to result in behavioral sensitization, or enhanced locomotor activity. Because there are similarities between effects of intermittent cocaine use in humans and sensitization in rats, understanding the neural mechanism underlying sensitization may provide insights into mechanisms of psychopathologies in humans.There is abundant evidence that the mesolimbic dopaminergic pathways, originating in the ventral tegmental area (VTA) and terminating in both nucleus accumbens (NAc) and prefrontal cortex (PFC), are critically important for development of sensitization to the motor-stimulating effects of cocaine. Evidence also suggests that changes in glutamate (Glu) transmission in the mesolimbic DA pathways are associated with sensitization to cocaine. In recent collaborative studies, we have shown that cocaine administration transiently decreases the density of nerve terminal glutamate immunolabeling within the NAc shell following withdrawal from continuous or intermittent cocaine administration. Locomotor activity was not assessed in either of these studies.

Lipopolysaccharide increases degradation of central monoamines: An in vivo microdialysis study in the nucleus accumbens and medial prefrontal cortex of mice

2014 ◽  
Vol 725 ◽  
pp. 55-63 ◽  
Author(s):  
Floor van Heesch ◽  
Jolanda Prins ◽  
Jan Pieter Konsman ◽  
Gerdien A.H. Korte-Bouws ◽  
Koen G.C. Westphal ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Nucleus Accumbens ◽  
Medial Prefrontal Cortex ◽  
In Vivo Microdialysis ◽  
Microdialysis Study

Stimulus-evoked dopamine overflow in the rat nucleus accumbens is decreased following chronic haloperidol administration: an in vivo voltammetric study

1995 ◽  
Vol 183 (1-2) ◽  
pp. 91-95 ◽  
Author(s):  
Karin J. Feasey-Truger ◽  
Christopher D. Earl ◽  
Christian Alzheimer ◽  
Gerrit ten Bruggencate
Keyword(s):  
Nucleus Accumbens ◽  
Voltammetric Study ◽  
Chronic Haloperidol ◽  
Rat Nucleus Accumbens

Olanzapine increases in vivo dopamine and norepinephrine release in rat prefrontal cortex, nucleus accumbens and striatum

1998 ◽  
Vol 136 (2) ◽  
pp. 153-161 ◽  
Author(s):  
Xi-Ming Li ◽  
Kenneth W. Perry ◽  
David T. Wong ◽  
F. P. Bymaster
Keyword(s):  
Prefrontal Cortex ◽  
Nucleus Accumbens ◽  
Norepinephrine Release
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