Development of lipophilic prodrugs of mitomycin C. I. Synthesis and antitumor activity of 1a-N-substituted derivatives with aromatic pro-moiety

1983 ◽  
Vol 15 (1) ◽  
pp. 49-59 ◽  
Author(s):  
Sasaki Hitoshi ◽  
Mukai Eiji ◽  
Hashida Mitsuru ◽  
Kimura Toshikiro ◽  
Sezaki Hitoshi
Keyword(s):  
Antitumor Activity ◽  
Mitomycin C ◽  
Lipophilic Prodrugs

scholarly journals Antitumor activity of lipophilic prodrugs of mitomycin C entrapped in liposome or O/W emulsion.

1984 ◽  
Vol 7 (2) ◽  
pp. 120-130 ◽  
Author(s):  
HITOSHI SASAKI ◽  
YOSHINOBU TAKAKURA ◽  
MITSURU HASHIDA ◽  
TOSHIKIRO KIMURA ◽  
HITOSHI SEZAKI
Keyword(s):  
Antitumor Activity ◽  
Mitomycin C ◽  
Lipophilic Prodrugs

scholarly journals Cellular interaction and in vitro antitumor activity of lipophilic mitomycin C prodrugs.

1987 ◽  
Vol 35 (9) ◽  
pp. 3784-3791
Author(s):  
SATOSHI MATSUMOTO ◽  
YOSHIE HAYASHI ◽  
MITSURU HASHIDA ◽  
HITOSHI SEZAKI
Keyword(s):  
Antitumor Activity ◽  
Mitomycin C ◽  
Cellular Interaction

scholarly journals Antitumor Activity of a Novel Double-Targeted System for Folate Receptor-Mediated Delivery of Mitomycin C

ACS Omega ◽  
2020 ◽  
Vol 5 (41) ◽  
pp. 26864-26870
Author(s):  
Yan Xu ◽  
Xiangmei Jin ◽  
Jun Zhang ◽  
Kun Wang ◽  
Xiaoyan Jin ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Mitomycin C ◽  
Folate Receptor

Antitumor activity of new liposomal prodrug of mitomycin C in multidrug resistant solid tumor: Insights of the mechanism of action

2007 ◽  
Vol 15 (7-8) ◽  
pp. 518-530 ◽  
Author(s):  
Samuel Zalipsky ◽  
Maha Saad ◽  
Radwan Kiwan ◽  
Elizabeth Ber ◽  
Ning Yu ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Mitomycin C ◽  
Mechanism Of Action ◽  
Solid Tumor ◽  
Multidrug Resistant

Development of lipophilic prodrugs of mitomycin C. II. Stability and bioactivation of 1a-N-substituted derivatives with aromatic pro-moiety

1983 ◽  
Vol 15 (1) ◽  
pp. 61-71 ◽  
Author(s):  
Sasaki Hitoshi ◽  
Mukai Eiji ◽  
Hashida Mitsuru ◽  
Kimura Toshikiro ◽  
Sezaki Hitoshi
Keyword(s):  
Mitomycin C ◽  
Lipophilic Prodrugs
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