scholarly journals Combined use of beta-adrenergic blocking agents and long-term cardiac pacing for patients with the long QT syndrome

1992 ◽  
Vol 20 (4) ◽  
pp. 830-837 ◽  
Author(s):  
Michael Eldar ◽  
Jerry C. Griffin ◽  
George F. Van Hare ◽  
Charles Witherell ◽  
Anil Bhandari ◽  
...  
2004 ◽  
Author(s):  
K. S. W. H. Hendriks ◽  
F. J. M. Grosfeld ◽  
A. A. M. Wilde ◽  
J. van den Bout ◽  
I. M. van Langen ◽  
...  

Mathematics ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. 1205
Author(s):  
Timur Gamilov ◽  
Philipp Kopylov ◽  
Maria Serova ◽  
Roman Syunyaev ◽  
Andrey Pikunov ◽  
...  

In this work we present a one-dimensional (1D) mathematical model of the coronary circulation and use it to study the effects of arrhythmias on coronary blood flow (CBF). Hydrodynamical models are rarely used to study arrhythmias’ effects on CBF. Our model accounts for action potential duration, which updates the length of systole depending on the heart rate. It also includes dependency of stroke volume on heart rate, which is based on clinical data. We apply the new methodology to the computational evaluation of CBF during interventricular asynchrony due to cardiac pacing and some types of arrhythmias including tachycardia, bradycardia, long QT syndrome and premature ventricular contraction (bigeminy, trigeminy, quadrigeminy). We find that CBF can be significantly affected by arrhythmias. CBF at rest (60 bpm) is 26% lower in LCA and 22% lower in RCA for long QT syndrome. During bigeminy, trigeminy and quadrigeminy, respectively, CBF decreases by 28%, 19% and 14% with respect to a healthy case.


1975 ◽  
Vol 18 (2) ◽  
pp. 148-152 ◽  
Author(s):  
Milton L. Hoefle ◽  
Stephen G. Hastings ◽  
Robert F. Meyer ◽  
Ruth M. Corey ◽  
Ann Holmes ◽  
...  

Circulation ◽  
1999 ◽  
Vol 100 (24) ◽  
pp. 2431-2436 ◽  
Author(s):  
Parvin C. Dorostkar ◽  
Michael Eldar ◽  
Bernard Belhassen ◽  
Melvin M. Scheinman

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