Effects of the spin trap α-phenyl n-tert-butyl nitrone on myocardial function and flow: A dose-response study in the open-chest dog and in the isolated rat heart

1993 ◽  
Vol 14 (3) ◽  
pp. 277-285 ◽  
Author(s):  
Xiao-Ying Li ◽  
Jian-Zhong Sun ◽  
Silvia Bradamante ◽  
Franceso Piccinni ◽  
Roberto Bolli
Keyword(s):  
Dose Response ◽  
Rat Heart ◽  
Spin Trap ◽  
Myocardial Function ◽  
Isolated Rat Heart ◽  
Tert Butyl ◽  
Open Chest ◽  
Dose Response Study ◽  
Isolated Rat

The Effects of Lipid Infusion on Myocardial Function and Bioenergetics in l-Bupivacaine Toxicity in the Isolated Rat Heart

2007 ◽  
Vol 104 (1) ◽  
pp. 186-192 ◽  
Author(s):  
Sebastian N. Stehr ◽  
J??rg C. Ziegeler ◽  
Annette Pexa ◽  
Reinhard Oertel ◽  
Andreas Deussen ◽  
...  
Keyword(s):  
Rat Heart ◽  
Myocardial Function ◽  
Isolated Rat Heart ◽  
Lipid Infusion ◽  
Bupivacaine Toxicity ◽  
Isolated Rat

Lipid effects on myocardial function in L-bupivacaine-induced toxicity in the isolated rat heart

2005 ◽  
Vol 30 (5) ◽  
pp. 5-5 ◽  
Author(s):  
S STEHR ◽  
J ZIEGELER ◽  
A PEXA ◽  
R OERTEL ◽  
A DEUSSEN ◽  
...  
Keyword(s):  
Rat Heart ◽  
Myocardial Function ◽  
Isolated Rat Heart ◽  
Isolated Rat

Effect of Perhexiline and Oxfenicine on Myocardial Function and Metabolism During Low-Flow Ischemia/Reperfusion in the Isolated Rat Heart

2000 ◽  
Vol 36 (6) ◽  
pp. 794-801 ◽  
Author(s):  
Jennifer A. Kennedy ◽  
Anthony J. Kiosoglous ◽  
Geraldine A. Murphy ◽  
Maria A. Pelle ◽  
John D. Horowitz
Keyword(s):  
Rat Heart ◽  
Myocardial Function ◽  
Ischemia Reperfusion ◽  
Isolated Rat Heart ◽  
Low Flow ◽  
Isolated Rat

Performance of hypothermic isolated rat heart at various levels of blood acid-base status

1984 ◽  
Vol 56 (6) ◽  
pp. 1526-1532 ◽  
Author(s):  
M. Sinet ◽  
M. Muffat-Joly ◽  
D. Henzel ◽  
G. Renault ◽  
J. J. Pocidalo
Keyword(s):  
Heart Rate ◽  
Rat Heart ◽  
Coronary Flow ◽  
Myocardial Function ◽  
Isolated Rat Heart ◽  
Acid Base ◽  
External Work ◽  
Myocardial Oxygenation ◽  
Acid Base Status ◽  
Isolated Rat

The effects of respiratory-induced pH variation on mechanical function and myocardial oxygenation of isolated, blood-perfused working rat hearts were studied in hypothermia (26 degrees C) and compared with control values (37 degrees C). In these experiments, the change of plasma pH during hypothermia was parallel to the change in pH of neutral water. At 37 degrees C, pH was varied from 7.15 to 7.62; heart rate increased with pH, both cardiac output and external work remaining unaltered. An increase in pH induced a decrease in coronary flow and an increase in the O2 arteriovenous difference. In hypothermia, hemodynamic performance and myocardial O2 consumption decreased proportionately with no change in cardiac efficiency. At 26 degrees C, the cardiac capacity to react to acid-base variations (pH from 7.34 to 7.86) was preserved, i.e., heart rate increased with pH. As at 37 degrees C, regulation of both coronary flow and myocardial oxygenation was maintained. The present data suggest that the myocardial function of a working isolated rat heart undergoing hypothermia was also preserved. Moderate variations in extracellular acid-base status during hypothermia did not impair either myocardial function or the O2 supply-to-demand ratio.

The effectiveness of postischemic oxypurinol administration upon myocardial function in the isolated rat heart

Resuscitation ◽  
1988 ◽  
Vol 16 (1) ◽  
pp. 31-43
Author(s):  
Stephen F. Badylak ◽  
Wm.D. Voorhees ◽  
Charles F. Babbs ◽  
Abby Simmons
Keyword(s):  
Rat Heart ◽  
Myocardial Function ◽  
Isolated Rat Heart ◽  
Isolated Rat

scholarly journals Insulin effects on myocardial function and bioenergetics in l-bupivacaine toxicity in the isolated rat heart

2007 ◽  
Vol 24 (4) ◽  
pp. 340-346 ◽  
Author(s):  
S. N. Stehr ◽  
A. Pexa ◽  
S. Hannack ◽  
A. Heintz ◽  
A. R. Heller ◽  
...  
Keyword(s):  
Rat Heart ◽  
Myocardial Function ◽  
Isolated Rat Heart ◽  
Bupivacaine Toxicity ◽  
Isolated Rat

DOSE RESPONSE TO CALCIUM AND HALOTHANE IN THE ISOLATED RAT HEART PREPARATION

1989 ◽  
Vol 71 (Supplement) ◽  
pp. A166
Author(s):  
T. Brussel ◽  
C. J. Cote ◽  
G. G. Stanford ◽  
B. Chernow
Keyword(s):  
Dose Response ◽  
Rat Heart ◽  
Isolated Rat Heart ◽  
Heart Preparation ◽  
Isolated Rat
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