Regional cerebral blood flow during the wisconsin card sorting test in normal subjects studied by xenon-133 dynamic SPECT: Comparison of absolute values, percent distribution values and covariance analysis

1993 ◽  
Vol 50 (3) ◽  
pp. 177-192 ◽  
Author(s):  
Stefano Marenco ◽  
Richard Coppola ◽  
David G. Daniel ◽  
Jeffrey R. Zigun ◽  
Daniel R. Weinberger
Keyword(s):  
Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Normal Subjects ◽  
Wisconsin Card Sorting Test ◽  
Card Sorting ◽  
Regional Cerebral Blood ◽  
Dynamic Spect ◽  
Wisconsin Card Sorting ◽  
Xenon 133 ◽  
Sorting Test

The Wisconsin Card Sorting Test (WCST) Performance in Normal Subjects: A Twin Study

1996 ◽  
Vol 34 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Arturo Campana ◽  
Fabio Macciardi ◽  
Orsola Gambini ◽  
Silvio Scarone
Keyword(s):  
Twin Study ◽  
Normal Subjects ◽  
Wisconsin Card Sorting Test ◽  
Card Sorting ◽  
Wisconsin Card Sorting ◽  
Sorting Test

Cortical blood flow during rest and Wisconsin Card Sorting Test performance in schizophrenia

2006 ◽  
Vol 156 (5-6) ◽  
pp. 179-184 ◽  
Author(s):  
Felipe Ortuño ◽  
Miguel Moreno-Íñiguez ◽  
Manuel Millán ◽  
César A. Soutullo ◽  
Raphael M. Bonelli
Keyword(s):  
Blood Flow ◽  
Test Performance ◽  
Wisconsin Card Sorting Test ◽  
Card Sorting ◽  
Cortical Blood Flow ◽  
Wisconsin Card Sorting ◽  
Sorting Test

Is the Mechanism of Prefrontal Hypofunction in Depression the Same as in Schizophrenia?

1993 ◽  
Vol 162 (2) ◽  
pp. 183-192 ◽  
Author(s):  
Karen Faith Berman ◽  
Allen R. Doran ◽  
David Pickar ◽  
Daniel R. Weinberger
Keyword(s):  
Blood Flow ◽  
Normal Subjects ◽  
Wisconsin Card Sorting Test ◽  
Pathophysiological Mechanism ◽  
Card Sorting ◽  
Depressed Patients ◽  
Regional Flow ◽  
Schizophrenic Patients ◽  
Testing Condition ◽  
Sorting Test

To test the hypothesis that depressed and schizophrenic patients have a common pathophysiological mechanism for hypofunction of the prefrontal cortex (‘hypofrontality’), we measured regional cortical blood flow (rCBF) in ten depressed patients, ten patients with schizophrenia, and 20 age- and sex-matched normal controls. Blood flow was measured during three different cognitive conditions: a resting state, a simple number-matching sensorimotor control task, and the Wisconsin Card Sorting test (WCS). The schizophrenic patients had lower prefrontal rCBF during the WCS. There were no differences in global or regional flow between the depressed patients and the normal subjects during any testing condition. Analysis of rCBF lateralisation showed that during the WCS normal subjects had relatively more left parietal blood flow than depressed patients, who had more right parietal blood flow. Since the testing condition that has most consistently revealed hypofrontality in schizophrenia (i.e. the WCS) was not associated with abnormal rCBF in the depressed patients, these data suggest that the pathophysiological mechanisms underlying prefrontal hypofunction in depression and schizophrenia are different.

Functional neural connectivity during performance of the Wisconsin Card Sorting Test: A path analysis of PET data from 86 normal subjects

NeuroImage ◽  
1998 ◽  
Vol 7 (4) ◽  
pp. S16
Author(s):  
A. Meyer-Lindenberg ◽  
J. Holt ◽  
J.D. Van Horn ◽  
G. Esposito ◽  
D.R. Weinberger ◽  
...  
Keyword(s):  
Path Analysis ◽  
Normal Subjects ◽  
Wisconsin Card Sorting Test ◽  
Neural Connectivity ◽  
Card Sorting ◽  
Wisconsin Card Sorting ◽  
Sorting Test
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