Diabetes and coronary circulation: From pathology to imaging

Author(s):  
Michael Y. Henein ◽  
Sergio Vancheri ◽  
Federico Vancheri
Keyword(s):  
1928 ◽  
Vol 65 (4) ◽  
pp. 357-373 ◽  
Author(s):  
G. V. Anrep ◽  
H. Häusler
Keyword(s):  

1976 ◽  
Vol 230 (4) ◽  
pp. 1037-1041 ◽  
Author(s):  
DR Strome ◽  
RL Clancy ◽  
NC Gonzalez

Isolated rabbit hearts were perfused with rabbit red cells suspended in Ringer solution. A small volume of perfusate was recirculated for 10 min at Pco2 of 33.4 +/- 0.9 or 150.8 +/- 7.5 mmHg. Hypercapnia resulted in an increase in perfusate HCO3- concentration that was smaller than that observed when isolated perfusate was equilibrated in vitro with the same CO2 tensions (delta HCO-3e = 1.6 mM, P less than 0.01). This difference is consistent with a net movement of HCO3- into or H+ out of the mycardial cell, and cannot be accounted for by dilution of HCO3- in the myocardial interstitium. Recirculation of perfusate through the coronary circulation at normal Pco2 for two consecutive 10-min periods was not followed by changes in perfusate HCO3- concentration. A high degree of correlation (r = 0.81) was observed between intracellular HCO-3e concentration and the corresponding delta HCO-3e in individual experiments. The results suggest that transmembrane exchange of H+ or HCO3- is a buffer mechanism for CO2 in the myocardial cell.


1996 ◽  
Vol 27 (2) ◽  
pp. 322
Author(s):  
Jay H. Traverse ◽  
Dianne L. Judd ◽  
Todd J. Pavek ◽  
Melanie J. Crampton ◽  
Robert J. Bache

2011 ◽  
Vol 12 (11) ◽  
pp. 811-813 ◽  
Author(s):  
Alessandro Zorzi ◽  
Giovanbattista Isabella ◽  
Umberto Cucchini ◽  
Giuseppe Tarantini ◽  
Sabino Iliceto ◽  
...  

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