ANIMAL REPRODUCTION AND CARCINOGENICITY STUDIES IN RELATION TO HUMAN SAFETY EVALUATION

Toxicology and Occupational Medicine ◽

10.1016/b978-0-444-00288-4.50011-6 ◽

1979 ◽

pp. 45-59 ◽

Author(s):

D.J. CLEGG

Keyword(s):

Safety Evaluation ◽

Animal Reproduction ◽

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part VI: When Salt and Sugar and Vegetables Are Positive, How Can Genotoxicity Data Serve to Inform Risk Assessment?

Toxicological Sciences ◽

10.1093/toxsci/kfm068 ◽

2007 ◽

Vol 98 (2) ◽

pp. 327-331 ◽

Author(s):

L. H. Pottenger ◽

J. S. Bus ◽

B. B. Gollapudi

Keyword(s):

Risk Assessment ◽

Safety Evaluation ◽

Toxicity Assessment ◽

Genetic Toxicity ◽

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part VII: Why Not Start with a Single Test: A Transformational Alternative to Genotoxicity Hazard and Risk Assessment

Toxicological Sciences ◽

10.1093/toxsci/kfm147 ◽

2007 ◽

Vol 99 (1) ◽

pp. 20-25 ◽

Author(s):

Warren W. Ku ◽

Jiri Aubrecht ◽

Robert J. Mauthe ◽

Robert H. Schiestl ◽

Albert J. Fornace

Keyword(s):

Risk Assessment ◽

Safety Evaluation ◽

Toxicity Assessment ◽

Single Test ◽

Genetic Toxicity ◽

Human Safety ◽

Hazard And Risk ◽

Hazard And Risk Assessment

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation

Toxicological Sciences ◽

10.1093/toxsci/kfl201 ◽

2006 ◽

Vol 96 (1) ◽

pp. 1-1 ◽

Author(s):

J. I. Goodman ◽

B. Gollapudi ◽

L. D. Lehman-McKeeman

Keyword(s):

Safety Evaluation ◽

Toxicity Assessment ◽

Genetic Toxicity ◽

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part II: Performances of the In Vitro Micronucleus Test Compared to the Mouse Lymphoma Assay and the In Vitro Chromosome Aberration Assay

Toxicological Sciences ◽

10.1093/toxsci/kfl193 ◽

2006 ◽

Vol 96 (2) ◽

pp. 214-217 ◽

Author(s):

Elisabeth Lorge ◽

Carine Lambert ◽

Véronique Gervais ◽

Nathalie Becourt-Lhote ◽

Jean-Luc Delongeas ◽

...

Keyword(s):

Chromosome Aberration ◽

Micronucleus Test ◽

Safety Evaluation ◽

Toxicity Assessment ◽

Genetic Toxicity ◽

Human Safety ◽

Chromosome Aberration Assay ◽

Mouse Lymphoma Assay ◽

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Editorial overview: Relevance of experimental toxicology in human safety evaluation

Current Opinion in Toxicology ◽

10.1016/j.cotox.2017.08.001 ◽

2017 ◽

Vol 3 ◽

pp. i-v

Author(s):

Colin Berry ◽

Lewis Smith

Keyword(s):

Safety Evaluation ◽

Experimental Toxicology ◽

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part IV:Recommendation of a Working Group of the Gesellschaft fuer Umwelt-Mutationsforschung (GUM) for a Simple and Straightforward Approach to Genotoxicity Testing

Toxicological Sciences ◽

10.1093/toxsci/kfm019 ◽

2007 ◽

Vol 97 (2) ◽

pp. 237-240 ◽

Author(s):

S. Pfuhler ◽

S. Albertini ◽

R. Fautz ◽

B. Herbold ◽

S. Madle ◽

...

Keyword(s):

Working Group ◽

Safety Evaluation ◽

Toxicity Assessment ◽

Genetic Toxicity ◽

Human Safety ◽

Genotoxicity Testing ◽

Straightforward Approach

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part III: The Comet Assay as an Alternative to In Vitro Clastogenicity Tests for Early Drug Candidate Selection

Toxicological Sciences ◽

10.1093/toxsci/kfl192 ◽

2007 ◽

Vol 97 (1) ◽

pp. 21-26 ◽

Author(s):

I. Witte ◽

U. Plappert ◽

H. de Wall ◽

A. Hartmann

Keyword(s):

Comet Assay ◽

Safety Evaluation ◽

Toxicity Assessment ◽

Candidate Selection ◽

Drug Candidate ◽

Genetic Toxicity ◽

Human Safety ◽

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part I: Early Screening for Potential Human Mutagens

Toxicological Sciences ◽

10.1093/toxsci/kfl191 ◽

2006 ◽

Vol 96 (1) ◽

pp. 16-20 ◽

Author(s):

D. Jacobson-Kram ◽

J. F. Contrera

Keyword(s):

Safety Evaluation ◽

Toxicity Assessment ◽

Early Screening ◽

Genetic Toxicity ◽

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A Probabilistic Approach for Human Safety Evaluation of Grounding Grids in the Transient Regime

IEEE Transactions on Power Delivery ◽

10.1109/tpwrd.2011.2179566 ◽

2012 ◽

Vol 27 (2) ◽

pp. 945-952 ◽

Author(s):

Ebrahim Amiri ◽

Seyed Hossein H. Sadeghi ◽

Rouzbeh Moini

Keyword(s):

Probabilistic Approach ◽

Safety Evaluation ◽

Transient Regime ◽

Human Safety ◽

Grounding Grids

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part IV: A Strategy in Genotoxicity Testing in Drug Development: Some Examples

Toxicological Sciences ◽

10.1093/toxsci/kfm056 ◽

2007 ◽

Vol 98 (1) ◽

pp. 39-42 ◽

Author(s):

E. Lorge ◽

V. Gervais ◽

N. Becourt-Lhote ◽

C. Maisonneuve ◽

J.-L. Delongeas ◽

...

Keyword(s):

Drug Development ◽

Safety Evaluation ◽

Toxicity Assessment ◽

Genetic Toxicity ◽

Human Safety ◽

Genotoxicity Testing

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