In Vitro Isolated Guinea Pig Brain

Author(s):  
MARCO DE CURTIS ◽  
LAURA LIBRIZZI ◽  
LAURA UVA
2017 ◽  
Vol 130 ◽  
pp. 21-26 ◽  
Author(s):  
Laura Uva ◽  
Davide Boido ◽  
Massimo Avoli ◽  
Marco de Curtis ◽  
Maxime Lévesque

1972 ◽  
Vol 126 (3) ◽  
pp. 575-585 ◽  
Author(s):  
C. J. Price ◽  
C. E. Rowe

1. Noradrenaline (1mm) and 5-hydroxytryptamine (1mm) stimulated the production of unesterified palmitate, oleate, stearate and arachidonate in nerve endings (synaptosomes) isolated from combined guinea-pig cerebral cortex and cerebellum. 2. Iproniazid phosphate (0.36mm) increased the concentrations of the same acids in osmotically ruptured synaptosomes. Further addition of 1mm-noradrenaline or 1mm-5-hydroxytryptamine reversed this increase. 3. Noradrenaline (0.01mm) stimulated the production of unesterified fatty acids in isolated synaptic membranes. 5-Hydroxytryptamine (0.01mm) stimulated the production of unesterified fatty acids in synaptic membranes and synaptic vesicles.


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