Is There Any Association Between Mammographic Features of Microcalcifications and Breast Cancer Subtypes in Ductal Carcinoma In Situ?

Author(s):  
Aydan Avdan Aslan ◽  
Serap Gültekin ◽  
Güldal Esendağli Yilmaz ◽  
Osman Kurukahvecioğlu
2016 ◽  
Vol 158 (1) ◽  
pp. 179-187 ◽  
Author(s):  
Shusma C. Doebar ◽  
Esther C. van den Broek ◽  
Linetta B. Koppert ◽  
Agnes Jager ◽  
Margreet. H. A. Baaijens ◽  
...  

2015 ◽  
Vol 39 (6) ◽  
pp. 983-986 ◽  
Author(s):  
Mi Young Kim ◽  
Hyeon Sook Kim ◽  
Nami Choi ◽  
Jung-Hyun Yang ◽  
Young Bum Yoo ◽  
...  

2018 ◽  
Vol 23 (4) ◽  
pp. 237-248 ◽  
Author(s):  
Hugo Villanueva ◽  
Sandra Grimm ◽  
Sagar Dhamne ◽  
Kimal Rajapakshe ◽  
Adriana Visbal ◽  
...  

Abstract Ductal carcinoma in situ (DCIS) is a non-obligate precursor to most types of invasive breast cancer (IBC). Although it is estimated only one third of untreated patients with DCIS will progress to IBC, standard of care for treatment is surgery and radiation. This therapeutic approach combined with a lack of reliable biomarker panels to predict DCIS progression is a major clinical problem. DCIS shares the same molecular subtypes as IBC including estrogen receptor (ER) and progesterone receptor (PR) positive luminal subtypes, which encompass the majority (60–70%) of DCIS. Compared to the established roles of ER and PR in luminal IBC, much less is known about the roles and mechanism of action of estrogen (E2) and progesterone (P4) and their cognate receptors in the development and progression of DCIS. This is an underexplored area of research due in part to a paucity of suitable experimental models of ER+/PR + DCIS. This review summarizes information from clinical and observational studies on steroid hormones as breast cancer risk factors and ER and PR as biomarkers in DCIS. Lastly, we discuss emerging experimental models of ER+/PR+ DCIS.


PLoS ONE ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. e0160835
Author(s):  
Hoe Suk Kim ◽  
Minji Jung ◽  
Sul Ki Choi ◽  
Woo Kyung Moon ◽  
Seung Ja Kim

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