Oleic Acid
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2022 ◽  
Vol 157 ◽  
pp. 106351
Alchris Woo Go ◽  
Yi Chang Xiao ◽  
Kristelle L. Quijote ◽  
Chintya Gunarto ◽  
Roxanne Kathlyn O. Alivio ◽  

2022 ◽  
Lisa Schuldt ◽  
Katrin von Brandenstein ◽  
Collin Jacobs ◽  
Judit Symmank

The initiation of a spatially and temporally limited inflammation is essential for tissue and bone remodeling by the periodontal ligament (PdL) located between teeth and alveolar bone. Obesity-associated hyperlipidemic changes may impair PdL fibroblast (PdLF) functions, disturbing their inflammatory response to mechanical stress such as those occurring during orthodontic tooth movement (OTM). Recently, we reported an attenuated pro inflammatory response of human PdLF (HPdLF) to compressive forces when stimulated with monounsaturated oleic acid (OA). Fatty acids, including OA, could serve as alternative source of acetyl-CoA, thereby affecting epigenetic histone marks such as histone 3 lysine acetylation (H3Kac) in a lipid metabolism-dependent manner. In this study, we therefore aimed to investigate the extent to which OA exerts its anti-inflammatory effect via changes in H3Kac. Six-hour compressed HPdLF showed increased H3Kac when cultured with OA. Inhibition of histone deacetylases resulted in a comparable IL10 increase as observed in compressed OA cultures. In contrast, inhibition of histone acetyltransferases, particularly p300/CBP, in compressed HPdLF exposed to OA led to an inflammatory response comparable to compressed control cells. OA-dependent increased association of H3Kac to IL10 promoter regions in force-stressed HPdLF further strengthened the assumption that OA exhibits its anti-inflammatory properties via modulation of this epigenetic mark. In conclusion, our study strongly suggests that obesity-related hyperlipidemia affect the functions of PdL cells via alterations in their epigenetic code. Since epigenetic inhibitors are already widely used clinically, they may hold promise for novel approaches to limit obesity-related risks during OTM.

Yishu Wang ◽  
Xiaokun Zhai ◽  
Liefeng Feng ◽  
Tingge Gao

Abstract The neutral and interlayer exciton originates from intralayer and interlayer coupling, respectively. Unlike neutral exciton, the interlayer excitons at room temperature are hard to observe and manipulate due to instability. In this work, we show the photoluminescence of WS$_2$ and MoS$_2$ neutral exciton can be improved by oleic acid passivation, allowing trion peaks to be observed at room temperature. More importantly, a 3-fold increase in peak intensity of interlayer excitons is achieved, and the energy peak is blue-shifted 107 meV. Our work paves the way to investigate excitons in two-dimensional transition metal dichalcogenides monolayers and heterostructures at room temperature.

2022 ◽  
Vol 1 (49) ◽  
pp. 5-5
Tatyana Zubkova ◽  

The aim of the study was to assess the effectiveness of the effect of natural nanoporous minerals together with organic waste from poultry farms on the yield of spring rapeseed, qualitative analysis of seeds and obtained samples of rapeseed oil. The experiments were carried out in 2019-2021 in the experimental field of the Yelets State University named after I.A. Bunin. The object of the study was the Rif spring rape variety. The highest productivity was observed in the variants with the introduction of zeolite (3 t / ha) in combination with organic waste 5 t / ha and 10 t / ha, which amounted to 34.4 c / ha and 34.9 c / ha, respectively. These options provided the maximum gross yield of protein (9.74 c / ha and 9.95 c / ha) and oil (13.95 c / ha and 14.10 c / ha). A positive effect from the use of natural zeolite as a fertilizer on the accumulation of oleic acid in the obtained rapeseed oil samples has been established. Keywords: SPRING RAPE, ZEOLITES, ORGANIC WASTE, YIELD, OIL QUALITY

Genome ◽  
2022 ◽  
pp. 1-12
Yang Xu ◽  
Fan Yan ◽  
Yu Zong ◽  
Jingwen Li ◽  
Han Gao ◽  

Vegetable oil is one of the most important components of human nutrition. Soybean (Glycine max) is an important oil crop worldwide and contains rich unsaturated fatty acids. Diacylglycerol acyltransferase (DGAT) is a key rate-limiting enzyme in the Kennedy pathway from diacylglycerol (DAG) to triacylglycerol (TAG). In this study, we conducted further research using T3 AhDGAT3 transgenic soybean. A high-performance gas chromatography flame ionization detector showed that oleic acid (18:1) content and total fatty acid content of transgenic soybean were significantly higher than those of the wild type (WT). However, linoleic acid (18:2) was much lower than that in the WT. For further mechanistic studies, 20 differentially expressed proteins (DEPs) and 119 differentially expressed metabolites (DEMs) were identified between WT (JACK) and AhDGAT3 transgenic soybean mature seeds using proteomic and lipidomics analyses. Combined proteomic and lipidomics analyses showed that the upregulation of the key DEP (lipase GDSL domain-containing protein) in lipid transport and metabolic process induced an increase in the total fatty acid and 18:1 composition, but a decrease in the 18:2 composition of fatty acids. Our study provides new insights into the deep study of molecular mechanism underlying the enhancement of fatty acids in transgenic soybeans, especially oleic acid and total fatty acid, which are enhanced by over-expression of AhDGAT3.

2022 ◽  
Vol 70 (1) ◽  
Tianxia Liu ◽  
Jian Qin ◽  
Jian Wang ◽  
Jing Li

Dilşat Bozdoğan Konuşkan

There are 97 local olive varieties registered in our country, and Saurani is an olive variety from originating Hatay/Altınözü. Hatay province, which ranks first in olive production in the Mediterranean Region, has very suitable climate and soil conditions for olive cultivation. The aim of this study is to investigate the effect of olive maturity on quality parameters such as free fatty acids, peroxide value and fatty acid composition of the oil obtained from the Saurani olive variety grown in Hatay. For this purpose, olive oil was obtained by mechanical method from olives collected from Saurani variety in 3 different maturity periods of the 2020 production season. In Saurani olive oil, free fatty acids and peroxide numbers were found in the range of 0.62-0.91 % (oleic acid) and 3.68-5.26 meq O2/kg respectively. The amount of free fatty acids increased with maturity. In Saurani olive oil were determined oleic acid in the range of 66.32%-68.79%, palmitic acid in the range of12.47-13.75%, linoleic acid in the range of 11.43-13.84%, stearic acid in the range of 3.16-3.42%, palmitoleic acid 1.12%-1.34%, linolenic acid 0.88-1.01% and arachidic acid 0.41-0.52. It was determined that decrease in oleic acid content and an increase in linoleic acid content with maturity. It has been determined that Saurani olive oil is within the limits specified in the Turkish Food Codex on Olive Oil and Pirina Olive Oil in terms of the examined properties.

Agronomy ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 122
Lara Abou Chehade ◽  
Luciana G. Angelini ◽  
Silvia Tavarini

The adoption of climate-resilient and resource-use efficient crop species and varieties is a key adaptation action for farmers in the face of climate change. Safflower, an emerging oilseed crop, has been recognized for its high oil quality and its favorable agronomic traits such as drought and cold tolerance, making it particularly suitable to Mediterranean conditions. A 2-year field study was carried out to evaluate the effects of the genotype and growing season on the crop phenology, seed and oil production, macronutrient accumulation and partitioning, and fatty acid composition of spring-sown safflower grown under rainfed conditions. The experiment was conducted during the 2012 and 2013 growing seasons on an alluvial deep loam soil (Typic Xerofluvent) at the Centre for Agri-environmental Research “E. Avanzi” of the University of Pisa (Pisa, Central Italy). Higher seed yield and yield components (plant density, plant height, branching, number of capitula per plant and seeds per capitulum) were found in almost all genotypes when the seeds were sown in mid-March 2012 compared to in late April 2013. More favorable conditions in 2012, i.e., early sowing date, higher precipitation, and quite mild temperatures, led to a better seed and oil yield and greater aboveground biomass and nitrogen uptake, with the highest amounts being removed by straw. Greater seed yield was found to be associated with a greater plant height and a higher number of capitula per plant. Oil content was negatively affected by the higher temperatures and the lower amounts of precipitation that occurred during the 2012 growing season. Seasonal variation in fatty acid composition depended on the genotype. Lower precipitation and higher temperatures during 2013 favored oleic acid content in high linoleic acid genotypes and linoleic acid in medium to high oleic acid genotypes. Among the genotypes, the linoleic-type Sabina and the oleic-type Montola 2000 performed the best in both seasons. The results, besides identifying promising safflower genotypes for spring sowing in the Mediterranean region and for future breeding programs, pointed out the importance of early sowing to contrast unfavorable environmental conditions during seed-filling, thus ensuring higher yields.

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