Introduction. Some cases of secondary adenocarcinoma developing in the
replaced bowel segment of urinary diversions have been reported so far.
Secondary adenocarcinoma develops 20 years after surgery in about 0.5% of
those in whom an ileal segment is used. There have been several reports in
the literature describing extensions of transitional cell carcinoma (TCC)
from the distal urether into an ileal conduit. Histology of loop tumor in 50%
was TCC. The site of tumors in the majority of cases is the area at the
uretheral orifices or the stoma. Case report. We presented a rare case of
transitional cell carcinoma in an orthotopic ileal neobladder 12 years after
radical cystoprostatectomy and ileal neobladder with the substitution by the
procedure Camey II. A 65-year-old man with high-grade urothelial carcinoma of
neobladder underwent partial resection of neobladder and right
nephroureterectomy. Pathological analysis revealed high-grade urothelial
carcinoma to the ileal neobladder (G II, Stage T2b). The patient died of
laryngeal cancer a year after the surgery. Conclusion. Surgery of tumors in
orthotopic neobladders is possible if diagnosed in time. In the presented
case surgery resulted only in a decrease in the capacity of the neobladder
without having an effect on the continence itself.