scholarly journals A Pilot Open-label Study of Aldose Reductase Inhibition with AT-001 (caficrestat) in Patients Hospitalized for COVID-19 Infection: Results from a Registry-based Matched-control Analysis

2021 ◽  
Vol 242 ◽  
pp. 153-154
Author(s):  
Juan Gaztanaga ◽  
Ravichandran Ramasamy ◽  
Ann Marie Schmidt ◽  
Glenn Fishman ◽  
Shoshana Shendelman ◽  
...  
1997 ◽  
Vol 41 (12) ◽  
pp. 2793-2796 ◽  
Author(s):  
H J Schaad ◽  
B G Petty ◽  
D M Grasela ◽  
B Christofalo ◽  
R Raymond ◽  
...  

This open-label study enrolled five subjects with biopsy-proven cirrhosis and moderate to severe hepatic impairment (Child-Pugh classification grade B or C) and five age- and gender-matched controls. All subjects received a single 40-mg oral dose of stavudine (d4T). Stavudine pharmacokinetics in subjects with hepatic impairment were similar to those in age- and gender-matched control subjects and were not substantially different from those previously observed in human immunodeficiency virus-infected patients. Based on these findings, stavudine use does not require modification of the dose or dosing interval for patients with liver disease.


2001 ◽  
Vol 120 (5) ◽  
pp. A392-A392 ◽  
Author(s):  
S NIVELONI ◽  
A CHERNAVSKY ◽  
S PEDREIRA ◽  
R MAZURE ◽  
H VAZQUEZ ◽  
...  

2006 ◽  
Vol 16 (4) ◽  
pp. 39-39
Author(s):  
B. L. Wiedermann

2017 ◽  
Vol 1 ◽  
pp. s95 ◽  
Author(s):  
Dee Anna Glaser ◽  
Adelaide A Hebert ◽  
Alexander Nast ◽  
William P Werschler ◽  
Stephen Shideler ◽  
...  

Abstract Not AvailableDisclosure: Study supported by Dermira.


2000 ◽  
Vol 12 (2) ◽  
pp. 97-100 ◽  
Author(s):  
Paul Goodnick ◽  
Cecilia Jorge ◽  
Thomas Hunter ◽  
Adarsh Kumar

2001 ◽  
Vol 13 (3) ◽  
pp. 153-158 ◽  
Author(s):  
Matthew Menza ◽  
Marc Lauritano ◽  
Lesley Allen ◽  
Melissa Warman ◽  
Frank Ostella ◽  
...  

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