Cystoid Macular Edema in Gyrate Atrophy of the Choroid and Retina: A Fluorescein Angiography and Optical Coherence Tomography Evaluation

2005 ◽  
Vol 140 (1) ◽  
pp. 147-149 ◽  
Author(s):  
Tâmara L. Oliveira ◽  
Rafael E. Andrade ◽  
Cristina Muccioli ◽  
Juliana Sallum ◽  
Rubens Belfort
2019 ◽  
Vol 2 ◽  
pp. 1 ◽  
Author(s):  
Anibal Martin Folgar ◽  
Jorge Oscar Zarate

We present a 57-year-old referred reduced visual acuity who was in treatment with paclitaxel for developing metastatic breast adenocarcinoma. Ophthalmoscopic examination, optical coherence tomography, and autofluorescence show the cystoid macular edema, but fluorescein angiography is normal, without leakage of dye in the late times. The patient responds well 8 weeks after stopping antineoplastic. Paclitaxel can cause cystoid macular edema and lifting a recovery both anatomical and functional of the macula.


2003 ◽  
Vol 66 (6) ◽  
pp. 771-774 ◽  
Author(s):  
Somaia Mitne ◽  
Augusto Paranhos Júnior ◽  
Ana Paula Silvério Rodrigues ◽  
Tércio Guia ◽  
Arnaldo Bordon ◽  
...  

2019 ◽  
Vol 14 (1) ◽  
pp. 43-47 ◽  
Author(s):  
M. Kanakis ◽  
I. Georgalas ◽  
T. Makatsoris ◽  
N. Pharmakakis

Purpose: To report a case of a 73-year-old man who presented with decreased visual acuity due to bilateral macular edema after paclitaxel administration for prostate cancer. Methods: The ophthalmic evaluation consisted of medical and ocular history, Best Corrected Visual Acuity, slit-lamp biomicroscopy and Spectral-domain optical coherence tomography / Fluorescein Angiography. Results: Optical Coherence Tomography and Fluorescein Angiography revealed silent cystoid macular edema. After consulting with the oncologist, the cessation of paclitaxel therapy was decided. The patient presented a gradual but steady resumption of the retinal edema, with complete restoration of normal retinal morphology and function within two months. The pathogenesis of the silent Cystoid Macular Edema (CME) is still unclear. Based on our case and a critical review of the previous observations and published data, we propose that the underlying cause of Taxane induced CME is the functional failure of Aquaporin mediated water transport at the level of retinal Intermediate and Deep capillary plexuses, and at lesser extent at the level of the Retinal Pigment Epithelium. Conclusion: Taxane induced silent CME should be attributed to the action of Taxanes on the microtubule guided aquaporin vesicles transport to the cell membrane. In our case of Taxane induced silent CME, withdrawal of the taxane was enough for complete recovery, and no additional treatment was needed.


Ophthalmology ◽  
2000 ◽  
Vol 107 (3) ◽  
pp. 593-599 ◽  
Author(s):  
Richard J Antcliff ◽  
Miles R Stanford ◽  
Devinder S Chauhan ◽  
Elizabeth M Graham ◽  
David J Spalton ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ali Osman Saatci ◽  
Hasan Can Doruk ◽  
Aylin Yaman

A 27-year-old man with progressive bilateral visual decline was diagnosed to have Bietti's crystalline dystrophy (BCD). Fluorescein angiography revealed bilateral petaloid type late hyperfluorescence implicating concurrent cystoid macular edema (CME). Optical coherence tomography exhibited cystoid foveal lacunas OU. During the follow-up of six years, intraretinal crystals reduced in amount but CME persisted angiographically and tomographically. CME is among the rare macular features of BCD including subfoveal sensorial detachment, subretinal neovascular membrane, and macular hole.


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