The Relationship of Optic Disk Cupping to Retinal Vein Occlusion: The Beaver Dam Eye Study

Retinal vein occlusions are believed to have a more favorable prognosis in young patients (<50 years old) due to spontaneous regression. However, 20% of patients have a poor outcome with severe neovascular complications. The causal relationship of occlusion in this age group is still unclear in most cases. There are reports of the development of a clinical picture of retinal vein occlusion in patients with COVID-19, the formation of which is most likely due to hypercoagulation syndrome. Purpose. To present a clinical case of post thrombotic retinopathy in a young patient after COVID-19. Material and methods. A clinical example of post thrombotic retinopathy in a young patient with retinal vein occlusion. Conclusion. Management of patients with retinal vein occlusion, especially at a young age, requires a comprehensive diagnostic approach with an assessment of systemic risk factors and mandatory assessment of the initial degree of retinal ischemia according to fluorescein angiography or Optical coherence tomography angiography. The clinical criteria for the increase in retinal ischemia are a decrease in central visual acuity, macular edema, ischemic area increase, and at the later stages - retinal neovascularization and / or of the anterior segment of the eye. COVID-19 did not affect significantly the change in the parameters of the coagulogram indices. However, its effect as an aggravating factor in a patient with a genetic predisposition to vascular and microvascular diseases cannot be excluded. Key words: OCTA-angiography, retinal neovascularization, post thrombotic retinopathy.

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Sea-fan neovascularization of the optic disk in branch retinal vein occlusion

Indian Journal of Ophthalmology - Case Reports ◽

10.4103/ijo.ijo_1461_21 ◽

2021 ◽

Vol 1 (4) ◽

pp. 879

Author(s):

Chitaranjan Mishra ◽

RenuPuthenvilayil Rajan ◽

NareshBabu Kannan ◽

Kim Ramasamy

Keyword(s):

Retinal Vein Occlusion ◽

Branch Retinal Vein Occlusion ◽

Optic Disk ◽

Vein Occlusion ◽

Sea Fan

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ARTERIOLAR MACROANEURYSM ON THE OPTIC DISK ASSOCIATED WITH BRANCH RETINAL VEIN OCCLUSION

Retinal Cases & Brief Reports ◽

10.1097/icb.0b013e318150d590 ◽

2009 ◽

Vol 3 (1) ◽

pp. 21-23 ◽

Cited By ~ 2

Author(s):

Toshiyuki Fujiwara ◽

Tomohiro Iida ◽

Kimimori Saito ◽

Ichiro Maruko

Keyword(s):

Retinal Vein Occlusion ◽

Branch Retinal Vein Occlusion ◽

Optic Disk ◽

Vein Occlusion

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OPTIC DISK ANALYSIS WITH HEIDELBERG RETINA TOMOGRAPHY IN PATIENTS WITH BRANCH RETINAL VEIN OCCLUSION

Retina ◽

10.1097/iae.0b013e318229b0dc ◽

2012 ◽

Vol 32 (5) ◽

pp. 985-989 ◽

Cited By ~ 2

Author(s):

Mehmet Citirik ◽

Kenan Sonmez ◽

Tulay Simsek ◽

Metin Unal

Keyword(s):

Retinal Vein Occlusion ◽

Branch Retinal Vein Occlusion ◽

Optic Disk ◽

Vein Occlusion

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The relationship between disorganitazion of the retinal inner layers and anti-vegf response in branch retinal vein occlusion

Journal of Retina-Vitreous ◽

10.37845/ret.vit.2020.29.10 ◽

2020 ◽

Vol 29 (1) ◽

pp. 53

Author(s):

Cemal OZSAYGILI ◽

Necati DURU

Keyword(s):

Retinal Vein Occlusion ◽

Branch Retinal Vein Occlusion ◽

Vein Occlusion ◽

Anti Vegf ◽

The Relationship

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Higher aqueous levels of matrix metalloproteinases indicated visual impairment in patients with retina vein occlusion after anti-VEGF therapy

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2019-315358 ◽

2019 ◽

pp. bjophthalmol-2019-315358 ◽

Cited By ~ 3

Author(s):

Yong Luo ◽

Jianbo Wan ◽

Chang Luo ◽

HengWei Liu ◽

YuFan Zhou ◽

...

Keyword(s):

Matrix Metalloproteinases ◽

Retinal Vein Occlusion ◽

Aqueous Humour ◽

Pearson Correlation ◽

Vein Occlusion ◽

Pearson Correlation Test ◽

Capillary Plexus ◽

Colour Photography ◽

Tomographic Angiography ◽

The Relationship

PurposeTo investigate the levels of matrix metalloproteinases (MMPs) in aqueous humour of patients with retinal vein occlusion (RVO) and the relationship between intraocular MMP levels and retinal lesion and visual prognosis.Materials and methods52 RVO patients, including 23 with central retinal vein occlusion (CRVO) and 29 with branch retinal vein occlusion (BRVO) and 20 participants with senile cataract were enrolled in this study. Retinal lesions were examined by fundus colour photography, fluorescein fundus angiography and optical coherence tomographic angiography. Sixty microliters of aqueous humour were collected during intravitreal anti-Vascular Endothelial Growth Factor (VEGF) injection or cataract surgery. The aqueous levels of MMP-1, MMP-2, MMP-7, MMP-9 and MMP-10 were measured using the Luminex xMAP multiplex assay. The relationship between MMP levels and clinical presentations was analysed by Pearson correlation test.ResultsThe aqueous humour levels of MMP-1, MMP-2, MMP-7 and MMP-9, but not MMP10 in RVO patients were significantly higher than those in people with cataract after adjusting for age. Further analysis of RVO subgroups showed that the aqueous humour level of MMP2 in CRVO was significantly higher than that in BRVO. The aqueous humour levels of MMP-1 and MMP-2 were positively correlated with superficial capillary plexus vessel density (SVD), whereas the aqueous humour levels of MMP-1 and MMP-7 were negatively correlated with visual improvement following treatment. No correlation between aqueous humour levels of MMP and disease duration and central retinal thickness was observed.ConclusionsRVO eyes had significantly higher intraocular levels of MMP-1, MMP-2, MMP-7 and MMP-9 than cataract eyes and the level of MMP2 appears to be related to the area of occlusion. Intraocular levels of MMP may positively affect SVD and negatively impact visual function in RVO.

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Laser Pan-Retinal Photocoagulation to Treat Central Retinal Vein Occlusion

Sriwijaya Journal of Ophthalmology ◽

10.37275/sjo.v2i2.13 ◽

2019 ◽

Vol 2 (2) ◽

pp. 40-52

Author(s):

Roland Iqbal ◽

AK Ansyori ◽

Ramzi Amin

Keyword(s):

Retinal Vein Occlusion ◽

Vision Loss ◽

Retinal Disease ◽

Optic Disk ◽

Dot Blot ◽

Grid Pattern ◽

Vein Occlusion ◽

Pan Retinal Photocoagulation ◽

Central Retinal Vein ◽

Retinal Photocoagulation

Introduction. Retinal Vein Occlusion (RVO) is the second most common retinal blood vessel disease after diabetic retinopathy. CRVO is an acute blockage of the central retinal vein that causes abnormalities in the retina, characterized by sudden decreased vision. Based on the potential for vision loss from this retinal disease, proper diagnosis and management is needed to prevent further complications. Case Presentation. A man, age 50 years old, a civil servant, came to the eye clinic of Mohammad Hosein Hospital on February 2017. The main complaint was vision of right eye suddenly blurred since 5 months before. Based on the above examination found decreased vision in one eye, with visual acuity better than 6/60 and no RAPD. The funduscopic examination above shows the presence of dilatation and tortousity in the central retinal vein, dot / blot bleeding and flame shaped hemorrhages in all quadrants, exudates, neovascularization of the retina and optic disk, and the presence of edema in the optic disc and macula. Conclusion. Management performed on these patients is by performing a Pan-Retinal Photocoagulation (PRP) laser and Grid-Pattern Photocoagulation. The selection of this therapy is based on the consideration that the patient has been suffering from CRVO for more than 3 months.

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