A proof-of-concept study of cascade screening for Familial Hypercholesterolemia in the US, adapted from the Dutch model

American Journal of Preventive Cardiology ◽

10.1016/j.ajpc.2021.100170 ◽

2021 ◽

pp. 100170

Author(s):

Mary P. McGowan ◽

Marina Cuchel ◽

Catherine D. Ahmed ◽

Amit Khera ◽

William S. Weintraub ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Proof Of Concept ◽

Cascade Screening ◽

Concept Study ◽

The Us ◽

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Safety and efficacy of evinacumab, a monoclonal antibody to ANGPTL3, in patients with homozygous familial hypercholesterolemia: A single-arm, open-label, proof-of-concept study

Atherosclerosis ◽

10.1016/j.atherosclerosis.2016.07.071 ◽

2016 ◽

Vol 252 ◽

pp. e254-e255 ◽

Author(s):

D. Gaudet ◽

D.A. Gipe ◽

É. Khoury ◽

R. Pordy ◽

W. Sasiela ◽

...

Keyword(s):

Monoclonal Antibody ◽

Familial Hypercholesterolemia ◽

Proof Of Concept ◽

Homozygous Familial Hypercholesterolemia ◽

Safety And Efficacy ◽

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Safety and efficacy of evinacumab, a monoclonal antibody to ANGPTL3, in patients with homozygous familial hypercholesterolemia: a single-arm, open-label, proof-of-concept study

Atherosclerosis ◽

10.1016/j.atherosclerosis.2017.06.057 ◽

2017 ◽

Vol 263 ◽

pp. e9 ◽

Author(s):

Daniel Gaudet ◽

Daniel Gipe ◽

Kees Hovingh ◽

Zahid Ahmad ◽

Marina Cuchel ◽

...

Keyword(s):

Monoclonal Antibody ◽

Familial Hypercholesterolemia ◽

Proof Of Concept ◽

Homozygous Familial Hypercholesterolemia ◽

Safety And Efficacy ◽

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A Cadaveric Model for Measuring Continuous Positive Airway Pressure (CPAP) in the Nasal Cavity and Paranasal Sinuses: A Proof of Concept Study

10.1055/s-0039-1679476 ◽

2019 ◽

Author(s):

Ryan Rimmer ◽

Chandala Chitguppi ◽

Hermes Garcia ◽

Ian Koszewski ◽

Gurston Nyquist ◽

...

Keyword(s):

Continuous Positive Airway Pressure ◽

Nasal Cavity ◽

Paranasal Sinuses ◽

Airway Pressure ◽

Positive Airway Pressure ◽

Proof Of Concept ◽

Concept Study ◽

Cadaveric Model

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HABITUATION AS PARAMETER FOR PREDICTION OF MENTAL DEVELOPMENT IN HEALTHY PRETERM INFANTS: AN EEG PROOF-OF-CONCEPT STUDY

10.26226/morressier.57d034d0d462b802923830ad ◽

2016 ◽

Author(s):

Antoinette DEPOORTER

Keyword(s):

Preterm Infants ◽

Mental Development ◽

Proof Of Concept ◽

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Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study

Case Medical Research ◽

10.31525/ct1-nct04115072 ◽

2019 ◽

Author(s):

Keyword(s):

Proof Of Concept ◽

Concept Study ◽

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A Proof of Concept Study of the Efficacy and Safety of Oral LAT8881 in Acute Migraine

Case Medical Research ◽

10.31525/ct1-nct04153409 ◽

2019 ◽

Author(s):

Keyword(s):

Acute Migraine ◽

Proof Of Concept ◽

Efficacy And Safety ◽

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A Mechanism Based Proof of Concept Study of the Effects of Duloxetine in the Treatment of Patients With Osteoarthritic Knee Pain

Case Medical Research ◽

10.31525/ct1-nct04224584 ◽

2020 ◽

Author(s):

Keyword(s):

Knee Pain ◽

Proof Of Concept ◽

Osteoarthritic Knee ◽

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Faculty Opinions recommendation of The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1091061.544445 ◽

2007 ◽

Author(s):

Ingvar Bjarnason

Keyword(s):

Coeliac Disease ◽

Proof Of Concept ◽

Concept Study ◽

Pharmacodynamic Effects

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Faculty Opinions recommendation of Effect of mesalazine on mucosal immune biomarkers in irritable bowel syndrome: a randomized controlled proof-of-concept study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1159760.621170 ◽

2009 ◽

Author(s):

Klaus Bielefeldt

Keyword(s):

Irritable Bowel Syndrome ◽

Proof Of Concept ◽

Concept Study ◽

Randomized Controlled ◽

Immune Biomarkers ◽

Irritable Bowel

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Faculty Opinions recommendation of Randomized, double-blind, placebo-controlled, proof-of-concept study of the cortical spreading depression inhibiting agent tonabersat in migraine prophylaxis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1161355.621864 ◽

2009 ◽

Author(s):

David Dodick ◽

Todd Schwedt

Keyword(s):

Cortical Spreading Depression ◽

Spreading Depression ◽

Migraine Prophylaxis ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

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