Faculty Opinions recommendation of Randomized, double-blind, placebo-controlled, proof-of-concept study of the cortical spreading depression inhibiting agent tonabersat in migraine prophylaxis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1161355.621864 ◽

2009 ◽

Author(s):

David Dodick ◽

Todd Schwedt

Keyword(s):

Cortical Spreading Depression ◽

Spreading Depression ◽

Migraine Prophylaxis ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study

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A randomized, double-blind, placebo-controlled proof of concept study to evaluate samidorphan in the prevention of olanzapine-induced weight gain in healthy volunteers

Schizophrenia Research ◽

10.1016/j.schres.2017.10.014 ◽

2018 ◽

Vol 195 ◽

pp. 245-251 ◽

Cited By ~ 16

Author(s):

Bernard L. Silverman ◽

William Martin ◽

Asli Memisoglu ◽

Lauren DiPetrillo ◽

Christoph U. Correll ◽

...

Keyword(s):

Weight Gain ◽

Healthy Volunteers ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study

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A multi-centre, double-blind, placebo-controlled, multiple-dose crossover proof of concept study to compare the efficacy of mefenamic acid administered vaginally and orally in healthy menstruating women with primary dysmenorrhoea requiring analgesia

http://isrctn.org/> ◽

10.1186/isrctn32847177 ◽

2012 ◽

Author(s):

David Bell

Keyword(s):

Mefenamic Acid ◽

Multiple Dose ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study ◽

Primary Dysmenorrhoea ◽

Menstruating Women

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Faculty Opinions recommendation of LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.724435768.793505748 ◽

2015 ◽

Author(s):

Vijay Kuchroo

Keyword(s):

Rheumatoid Arthritis ◽

Monoclonal Antibody ◽

Phase I ◽

Interleukin 17 ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study

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Escitalopram for Severe Asthma and Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Proof-of-Concept Study

Psychosomatics ◽

10.1016/j.psym.2011.07.009 ◽

2012 ◽

Vol 53 (1) ◽

pp. 75-80 ◽

Cited By ~ 19

Author(s):

E. Sherwood Brown ◽

Christina Howard ◽

David A. Khan ◽

Thomas J. Carmody

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Severe Asthma ◽

Proof Of Concept ◽

Major Depressive ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study

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OP0047 A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Proof-Of-Concept Study to Evaluate the Efficacy and Safety of Sirukumab in Patients with Active Lupus Nephritis

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.3974 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 78.2-78 ◽

Cited By ~ 7

Author(s):

R. van Vollenhoven ◽

C. Aranow ◽

B. Rovin ◽

C. Wagner ◽

B. Zhou ◽

...

Keyword(s):

Lupus Nephritis ◽

Phase 2 ◽

Proof Of Concept ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study ◽

Active Lupus Nephritis ◽

Active Lupus

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Effect of Denosumab on Osteolytic Lesion Activity after Total Hip Arthroplasty: A Single-Centre, Randomised, Double-Blind, Placebo-Controlled, Proof-of-Concept Study

SSRN Electronic Journal ◽

10.2139/ssrn.3679988 ◽

2020 ◽

Author(s):

Mohit Mahatma ◽

Raveen Jayasuriya ◽

David Hughes ◽

Nigel Hoggard ◽

Simon Buckley ◽

...

Keyword(s):

Total Hip Arthroplasty ◽

Hip Arthroplasty ◽

Osteolytic Lesion ◽

Proof Of Concept ◽

Single Centre ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study ◽

Total Hip

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58 FINAL RESULTS – RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED SAFETY, ANTI-VIRAL PROOF-OF-CONCEPT STUDY OF MIRAVIRSEN, AN OLIGONUCLEOTIDE TARGETING MIR-122, IN TREATMENT-NAIVE PATIENTS WITH GENOTYPE 1 CHRONIC HCV INFECTION

Journal of Hepatology ◽

10.1016/s0168-8278(12)60072-5 ◽

2012 ◽

Vol 56 ◽

pp. S26 ◽

Cited By ~ 17

Author(s):

H.W. Reesink ◽

H.L.A. Janssen ◽

S. Zeuzem ◽

E. Lawitz ◽

M. Rodriguez-Torres ◽

...

Keyword(s):

Hcv Infection ◽

Proof Of Concept ◽

Genotype 1 ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study ◽

Treatment Naïve ◽

Chronic Hcv Infection ◽

Chronic Hcv

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A phase II, multi-centre, randomised, double-blind, placebo-controlled, parallel group, proof of concept study to compare the efficacy, safety and tolerability of PSD502, delivered topically onto the upper vagina and cervix, to placebo in controlling discomfort/pain intensity in subjects undergoing outpatient hysteroscopy

http://isrctn.org/> ◽

10.1186/isrctn46090514 ◽

2012 ◽

Author(s):

Wlodzimierz Baranowski

Keyword(s):

Pain Intensity ◽

Phase Ii ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study ◽

Parallel Group ◽

Outpatient Hysteroscopy

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P372. A multicentre, double-blind, placebo-controlled, parallel group, proof of concept study to evaluate the efficacy, safety and tolerability of the S1P receptor modulator KRP203 in subjects with moderately active refractory ulcerative colitis*

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jjw019.491 ◽

2016 ◽

Vol 10 (suppl 1) ◽

pp. S285.2-S286

Keyword(s):

Ulcerative Colitis ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study ◽

Receptor Modulator ◽

Parallel Group ◽

S1p Receptor

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A randomized, double-blind, placebo-controlled proof-of-concept study of ondansetron for bipolar and related disorders and alcohol use disorder

European Neuropsychopharmacology ◽

10.1016/j.euroneuro.2020.12.006 ◽

2021 ◽

Author(s):

E. Sherwood Brown ◽

Meagan McArdle ◽

Jayme Palka ◽

Collette Bice ◽

Elena Ivleva ◽

...

Keyword(s):

Alcohol Use ◽

Alcohol Use Disorder ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study

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