Impact of Body Mass Index on Early Outcome and Late Survival in Patients Undergoing Coronary Artery Bypass Grafting or Valve Surgery or Both

Background: The association of obesity with postoperative bleeding volume and transfusions after coronary artery bypass grafting (CABG) is not clear. We evaluated the effects of body mass index (BMI) on bleeding volume and transfusions in patients undergoing on-pump CABG. Methods: We investigated 1,050 patients, aged 24 years to 83 years, who underwent isolated, primary CABG with cardiopulmonary bypass (CPB) at Fuwai Hospital, Chinese Academy of Medical Sciences, from September 2017 to July 2018. We recorded preoperative medical and laboratory coagulation parameters, intraoperative data, and postoperative bleeding volume for 24 hours following surgery. Primary endpoint was bleeding volume within 24 hours and transfusions after surgery. We analyzed the correlation between bleeding volume within 24 hours and transfusions after surgery and preoperative data with univariate and multivariate linear regression and logistic regression. Results: Old age significantly increased postoperative transfusions (OR = 1.035 95% CI 1.013-1.058, P = .002), whereas higher BMI (OR = 0.897 95% CI 0.848-0.949, P < .001) and higher hemoglobin (HGB) (OR = 0.966 95% CI 0.954-0.978, P < 0.001) decreased postoperative transfusions. And, BMI independently was correlated with bleeding volume after multivariate regression analysis (B = -0.257, P < .001). Conclusions: Our findings suggest higher BMI may reduce postoperative bleeding volume and transfusion rate, thus such patients may save blood products during on-pump CABG.

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Changes in Body Mass Index and Late Postoperative Outcomes in Elderly Coronary Artery Bypass Grafting Patients: A Follow-up Study

Biological Research For Nursing ◽

10.1177/1099800404264538 ◽

2004 ◽

Vol 6 (1) ◽

pp. 24-36 ◽

Cited By ~ 14

Author(s):

Rose Ann DiMaria-Ghalili

Keyword(s):

Body Mass Index ◽

Coronary Artery ◽

Coronary Artery Bypass Grafting ◽

Coronary Artery Bypass ◽

Body Mass ◽

Artery Bypass ◽

Bypass Grafting ◽

Artery Bypass Grafting ◽

Over Time

The purpose of this study was to describe the extent to which late postoperative health outcomes vary as a function of change in body mass index (BMI) in persons 65 years of age undergoing elective coronary artery bypass grafting (CABG). The mean age of the 90 persons in the original sample was 72.27 (±4.85) years. At follow-up (x = 18.73,s = 2.56 months postsurgery), 90% (n = 79 alive,n = 2 deceased, proxy completed interview) were contacted; 73% (n = 59) completed the telephone interview; and 9% (n = 8) were alive but lost to follow-up. BMI (kg/m2) was calculated from self-reported weight at follow-up. Outcomes included the Physical Component Summary (PCS) scale of the SF-36 Health Survey and readmission data. Thex (s ) for BMI at preoperative, postoperative, postdischarge, and follow-up were 28.1 (4.9) kg/ m2 , 28.76 (4.9) kg/m2, 27.11 (4.8) kg/m2, and 27.95 (4.7) kg/m2, respectively. BMI changed over time,P < 0.05. Those who were readmitted lost more weight between preoperative and postdischarge than those who were not readmitted (x BMI = –2.26 vs.x BMI = –1.35),t = 2.17,df = 27.05,P = 0.04. Those who lost less weight between preoperative and postdischarge were less likely to be readmitted,.2 = 5.755 (1),P = 0.02, with 25% sensitivity and 92% specificity. Thex (sx) for PCS at preoperative, postdischarge, and follow-up were 36.93 (1.62), 35.72 (1.27), and 42.26 (1.45), respectively, reflecting change over time,F = 11.43 (2),P < 0.001. At follow-up, older elective CABG patients do not appear to regain weight lost between preoperative and postdischarge; however, self-reported physical health is improved. Also, initial weight loss is related to readmissions.

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