Role of Implantable Cardioverter-Defibrillators in Patients With Methadone-Induced Long QT Syndrome

2008 ◽  
Vol 101 (2) ◽  
pp. 209-211 ◽  
Author(s):  
Anshul M. Patel ◽  
Jagmeet P. Singh ◽  
Jeremy N. Ruskin
Keyword(s):  
Long Qt Syndrome ◽  
Implantable Cardioverter Defibrillators ◽  
Long Qt ◽  
Qt Syndrome ◽  
Cardioverter Defibrillators

scholarly journals Implantable cardioverter-defibrillators in patients with long QT syndrome: a multicentre study

2018 ◽  
pp. 1687-1696 ◽  
Author(s):  
Agnieszka Zienciuk-Krajka ◽  
Maciej Sterliński ◽  
Artur Filipecki ◽  
Radosław Owczuk ◽  
Jacek Bednarek ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Long Qt Syndrome ◽  
Implantable Cardioverter Defibrillators ◽  
Long Qt ◽  
Qt Syndrome ◽  
Cardioverter Defibrillators

scholarly journals Effectiveness of Implantable Cardioverter-Defibrillators to Reduce Mortality in Patients With Long QT Syndrome

2021 ◽  
Vol 78 (21) ◽  
pp. 2076-2088 ◽  
Author(s):  
Meng Wang ◽  
Derick R. Peterson ◽  
Spencer Rosero ◽  
Scott McNitt ◽  
David Q. Rich ◽  
...  
Keyword(s):  
Long Qt Syndrome ◽  
Implantable Cardioverter Defibrillators ◽  
Long Qt ◽  
Qt Syndrome ◽  
Cardioverter Defibrillators

Use of Implantable Cardioverter-Defibrillators in the Congenital Long QT Syndrome

1996 ◽  
Vol 78 (6) ◽  
pp. 703-706 ◽  
Author(s):  
William J. Groh ◽  
Michael J. Silka ◽  
Ronald P. Oliver ◽  
Blair D. Halperin ◽  
John H. McAnulty ◽  
...  
Keyword(s):  
Long Qt Syndrome ◽  
Implantable Cardioverter Defibrillators ◽  
Long Qt ◽  
Qt Syndrome ◽  
Cardioverter Defibrillators ◽  
Congenital Long Qt Syndrome

scholarly journals Elucidating the role of Cavin1 in drug-induced long QT syndrome (diLQTS)

2021 ◽  
Vol 13 (2) ◽  
pp. 228-229
Author(s):  
Z. Al Sayed ◽  
C. Pereira ◽  
C. Jouve ◽  
J. Hulot
Keyword(s):  
Long Qt Syndrome ◽  
Long Qt ◽  
Drug Induced ◽  
Qt Syndrome

scholarly journals Computational Analysis of Coronary Blood Flow: The Role of Asynchronous Pacing and Arrhythmias

Mathematics ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. 1205
Author(s):  
Timur Gamilov ◽  
Philipp Kopylov ◽  
Maria Serova ◽  
Roman Syunyaev ◽  
Andrey Pikunov ◽  
...  
Keyword(s):  
Heart Rate ◽  
Blood Flow ◽  
Coronary Blood Flow ◽  
Long Qt Syndrome ◽  
Premature Ventricular Contraction ◽  
Cardiac Pacing ◽  
Long Qt ◽  
Computational Evaluation ◽  
Qt Syndrome

In this work we present a one-dimensional (1D) mathematical model of the coronary circulation and use it to study the effects of arrhythmias on coronary blood flow (CBF). Hydrodynamical models are rarely used to study arrhythmias’ effects on CBF. Our model accounts for action potential duration, which updates the length of systole depending on the heart rate. It also includes dependency of stroke volume on heart rate, which is based on clinical data. We apply the new methodology to the computational evaluation of CBF during interventricular asynchrony due to cardiac pacing and some types of arrhythmias including tachycardia, bradycardia, long QT syndrome and premature ventricular contraction (bigeminy, trigeminy, quadrigeminy). We find that CBF can be significantly affected by arrhythmias. CBF at rest (60 bpm) is 26% lower in LCA and 22% lower in RCA for long QT syndrome. During bigeminy, trigeminy and quadrigeminy, respectively, CBF decreases by 28%, 19% and 14% with respect to a healthy case.

Long QT syndrome: beyond making a diagnosis

2020 ◽  
pp. 189-200
Author(s):  
Gabrielle Norrish ◽  
Juan Pablo Kaski
Keyword(s):  
Long Qt Syndrome ◽  
Ventricular Arrhythmias ◽  
Beta Blockers ◽  
Psychological Impact ◽  
Population Screening ◽  
Implantable Cardioverter Defibrillators ◽  
Long Qt ◽  
Arrhythmic Death ◽  
Arrhythmic Event ◽  
Qt Syndrome

Long QT syndrome (LQTS) is an uncommon, but important, cause of ventricular arrhythmias. The diagnosis is straightforward in symptomatic patients with marked QT prolongation on a resting 12-lead electrocardiogram (ECG). However, in many patients, the ECG findings are dynamic, and to make the diagnosis, clinicians need to be aware of suggestive features. The greatest challenge in managing these patients is risk stratification for a sudden arrhythmic event. Beta-blockers have been shown to reduce the risk for ventricular arrhythmias in all genotype-positive patients, regardless of 12-lead ECG findings. For patients in whom beta-blockers are contraindicated, left cardiac sympathetic denervation may be a useful therapy. Implantable cardioverter–defibrillators have a role to play in preventing sudden cardiac death, although their use should be balanced with associated complications and psychological impact. Population screening for LQTS remains controversial. Screening of first-degree relatives in sudden arrhythmic death syndrome is recommended, but population screening is not currently undertaken in the United Kingdom.

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