scholarly journals Patent Foramen Ovale Closure for Secondary Prevention of Cryptogenic Stroke: Updated Meta-Analysis of Randomized Clinical Trials

2018 ◽  
Vol 131 (5) ◽  
pp. 575-577 ◽  
Author(s):  
Muthiah Vaduganathan ◽  
Arman Qamar ◽  
Ankur Gupta ◽  
Navkaranbir Bajaj ◽  
Harsh B. Golwala ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Secondary Prevention ◽  
Patent Foramen Ovale ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

scholarly journals Patent foramen ovale closure versus medical therapy after cryptogenic stroke: An updated meta-analysis of all randomized clinical trials

2019 ◽  
Vol 26 (1) ◽  
pp. 47-55 ◽  
Author(s):  
Babikir Kheiri ◽  
Ahmed Abdalla ◽  
Mohammed Osman ◽  
Sahar Ahmed ◽  
Mustafa Hassan ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Medical Therapy ◽  
Patent Foramen Ovale ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

Secondary prevention of cryptogenic stroke in patients with patent foramen ovale: a systematic review and meta-analysis

2018 ◽  
Vol 13 (8) ◽  
pp. 1287-1303 ◽  
Author(s):  
Elisa Maria Fiorelli ◽  
Tiziana Carandini ◽  
Delia Gagliardi ◽  
Viviana Bozzano ◽  
Mattia Bonzi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Secondary Prevention ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

Patent foramen ovale closure versus medical therapy for prevention of recurrent cryptogenic embolism: updated meta-analysis of randomized clinical trials

2018 ◽  
Vol 107 (9) ◽  
pp. 788-798 ◽  
Author(s):  
Brunilda Alushi ◽  
Alexander Lauten ◽  
Salvatore Cassese ◽  
Roisin Colleran ◽  
Stefanie Schüpke ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Medical Therapy ◽  
Patent Foramen Ovale ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Foramen Ovale

scholarly journals Update on the Management of Patent Foramen Ovale in 2017: Indication for Closure and Literature Review

2017 ◽  
Vol 11 (2) ◽  
pp. 75 ◽  
Author(s):  
Kimberly Atianzar ◽  
Peter Casterella ◽  
Ming Zhang ◽  
Rahul Sharma ◽  
Sameer Gafoor ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Patent Foramen Ovale ◽  
Randomized Clinical Trials ◽  
Decompression Sickness ◽  
Cryptogenic Stroke ◽  
Closure Device ◽  
Foramen Ovale ◽  
Stroke Patients ◽  
Consensus Statements ◽  
Pfo Closure

Patent foramen ovale (PFO) is a common congenital abnormality with a high prevalence of approximately 25 % in the general population and an even higher incidence of about 40 % in the cryptogenic stroke population. PFO closure in cryptogenic stroke patients as a treatment modality for the secondary prevention of recurrent stroke has been much debated and studied. Several completed randomized clinical trials sought to answer the question of whether PFO closure is beneficial for cryptogenic stroke patients. Until the most recent of these trials, no significant benefit had been demonstrated. Based on newer evidence, in October 2016 the US Food and Drug Administration approved the first dedicated closure device for PFO. This review article describes the association between PFO and cryptogenic stroke, reviews current diagnostic modalities of PFO assessment, discusses management approaches, and reviews randomized clinical trials, practice guidelines, and consensus statements. Associations between PFO and other conditions such as migraine headaches, platypnea-orthodeoxia syndrome, and decompression sickness in divers are also briefly reviewed.

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