scholarly journals Parathyroid hormone level after total thyroidectomy using conventional versus harmonic focus technique: Prospective randomized study

2021 ◽  
pp. 103176
Author(s):  
Hany Abdelfatah Elhady ◽  
Rasha Abd Elaziz Abd Elghany ◽  
Mohammed Shehata Zarad
2020 ◽  
Vol 23 (1) ◽  
pp. 5-10
Author(s):  
Islam MS ◽  
Sultana T ◽  
Paul D ◽  
Huq AHMZ ◽  
Ferdoushi S ◽  
...  

Background: Postoperative hypoparathyroidism is a common complication after total thyroidectomy. It is necessary to diagnose hypoparathyroidism immediately after total thyroidectomy for minimizing complications. Objective: The objective of this study was to measure and to evaluate the serum parathyroid hormone level in total thyroidectomy patients. Methods: This prospective observational study was carried out in the Department of Clinical Pathology in collaboration with Department of Surgery & Department of Otolaryngology of BSMMU and Department of Otolaryngology of DMCH, Dhaka, during the period of September 2010 to August 2011. Results: Total 65 patients were studied irrespective of age and sex. Decreased serum PTH was found in 9 cases and normal parathyroid hormone was found in 56 cases. Male was 16.0% and female was 84.0%. Females were predominant. The incidence of hypoparathyroidism was 41.5%. Asymptomatic hypoparathyroidism was found in 8 and symptomatic hypoparathyroidism was found in 1 cases. Decreased serum PTH was developed mostly in malignant thyroid diseases. In relation to preoperative PTH values, intraoperative PTH levels were lower from 5.48% to 90.0%, (mean±SD in percentage is 65.3±16.7, p=.001) which is significant in paired t test. The mean difference of intraoperative (20 minutes after total thyroidectomy), parathyroid hormone levels were statistically significant (p<0.05) between patient with decreased parathyroid hormone and patient with normal parathyroid hormone in unpaired t-test. Conclusion: Serum parathyroid hormone level significantly decreased 20 minutes after total thyroidectomy. If clinical sign symptoms of hypoparathyroidism are not developed in postoperative period, patient is safe and can be discharged from hospital. Bangladesh J Otorhinolaryngol; April 2017; 23(1): 5-10


2018 ◽  
Vol 5 (3) ◽  
pp. 1100
Author(s):  
Naveen Arnepalli ◽  
Chethan Kishanchand ◽  
Balaji Jayasankar

Background: Detecting post-operative hypocalcaemia following total thyroidectomy using serum parathyroid hormone levels would help in an earlier and a definitive treatment plan in treating hypocalcaemia.Methods: This was a prospective interventional study done in a tertiary care teaching hospital. This was mainly done to assess the post-operative hypocalcemia following total thyroidectomy using parathyroid hormone levels and to assess the correlation between the two. With a baseline levels recorded patients underwent a post-operative evaluation of parathyroid hormone 1 hour after total thyroidectomy and serum calcium levels on day 1, 2, 3 and 4 after surgery. The same was statically analyzed to find a correlation between parathyroid hormone levels and the degree of hypocalcemia and evaluated to see if parathyroid hormone was a reliable clinical indicator.Results: A total of 43 patients were included in the study and the parathyroid hormone levels were assessed following surgery, the same was plotted statistically. Sensitivity of parathyroid hormone drop by 75% in predicting hypocalcaemia was 95%. 50% drop in parathyroid hormone levels was a sensitive predictor of hypocalcaemia. A PTH value of less than 15.1pg/ml was highly specific and sensitive indicator of hypocalcaemia.Conclusions: Parathyroid hormone Assay following total thyroidectomy is reliable for early prediction of hypocalcaemia. Patients with a parathyroid hormone level <9pg/ml or with 75% drop in parathyroid hormone level are at a high risk for hypocalcaemia and would require calcium supplementation.


2011 ◽  
Vol 9 (1) ◽  
Author(s):  
Qingqing He ◽  
Dayong Zhuang ◽  
Luming Zheng ◽  
Peng Zhou ◽  
Jixin Chai ◽  
...  

2018 ◽  
Vol 41 (3) ◽  
pp. 222-228 ◽  
Author(s):  
Kemal Arslan ◽  
Bulent Erenoglu ◽  
Osman Dogru ◽  
Gultekin Ovet ◽  
Ersin Turan ◽  
...  

2021 ◽  
pp. 81-83
Author(s):  
Harish Kumar Reddy Kata ◽  
Abhay Kumar Abhay Kumar ◽  
Sudhir Shinde ◽  
Nithish K

Thyroid and parathyroid are anatomically close to each other. Blood supply to parathyroid may get cut off inadvertently or all parathyroid tissue may get removed removed during near total or total thyroidectomy.As a result of near total and total thyroidectomy it may lead to hypocalcemia crisis post-operatively causing tingling, numbness, tetany, neuro-muscular dysfunction.Hypocalcemia is the most common etiological factor for prolonged hospitalization in patients undergoing total thyroidectomy.Recent studies concludes that, hypocalcemia can be prevented by assessing S. PTH levels pre-operatively and intra-operatively one hour after removing the gland.This study includes 30 patients, who underwent near total and total thyroidectomy from August 2018-July2020 with thyroid swelling where indicated for surgery.Patients who underwent total thyroidectomy for malignancy (10 out of 30) developed hypocalcemia, this attributed to the extensive surgical dissection performed in malignant disorders in order to obtain tumour clearance.For the Stratication of thyroidectomy patients who may develop hypocalcemia into low and high risk category, a single 1-hour post-thyroidectomy PTH level is very useful.


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