Comparison of Clinical and Neurophysiologic Responses to Intrathecal Baclofen Bolus Administration in Moderate-to-Severe Spasticity After Acquired Brain Injury

2005 ◽  
Vol 86 (9) ◽  
pp. 1801-1806 ◽  
Author(s):  
Dobrivoje S. Stokic ◽  
Stuart A. Yablon ◽  
Antonio Hayes
1997 ◽  
Vol 87 (3) ◽  
pp. 415-419 ◽  
Author(s):  
Jay M. Meythaler ◽  
Anne McCary ◽  
Mark N. Hadley

✓ Twelve consecutive patients with severe spasticity and hypertonia following acquired brain injury were treated with continuous intrathecal infusion of baclofen via an implanted, programmable infusion pump—catheter system for a minimum of 3 months. In every case intrathecal baclofen therapy resulted in a statistically significant reduction in upper- and lower-extremity tone, spasm frequency, and reflexes, contributing to improved functional abilities. There were no untoward side effects or complications associated with treatment. This preliminary assessment indicates that intrathecal administration of baclofen is effective in treating the disabling spasticity caused by acquired brain injury in selected patients.


2021 ◽  
pp. 76-78
Author(s):  
Anand Sharma ◽  
Yashbir Dewan

Management of severe spasticity following penetrating brain injury is often a difcult problem. Orally administered medications generally offer limited benets. Intrathecally administered baclofen has been shown to be effective in patients with spasticity caused by spinal cord injury and stroke, however, the effectiveness of ITB for spasticity related to penetrating brain injury is not well established. We reported two cases of spastic hypertonia following gunshot injury to brain with brief review of literature upon role of intrathecal baclofen pump (ITB) in cortical spastic hypertonia


Medicine ◽  
2017 ◽  
Vol 96 (34) ◽  
pp. e7472 ◽  
Author(s):  
Young Kwon Yoon ◽  
Kil Chan Lee ◽  
Han Eol Cho ◽  
Minji Chae ◽  
Jin Woo Chang ◽  
...  

PM&R ◽  
2016 ◽  
Vol 8 (9) ◽  
pp. S282
Author(s):  
Mithra B. Maneyapanda ◽  
Zachary McCormick ◽  
Christina M. Marciniak ◽  
Christopher D. Reger

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