Poster 147: Predictors of Outcome in Transforaminal Epidural Steroid Injections for Patients With Lumbosacral Herniated Nucleus Pulposus: A Retrospective Chart Review

2008 ◽  
Vol 89 (11) ◽  
pp. e67
Author(s):  
Kermit W. Fox ◽  
John Chae ◽  
Alma J. Garcia ◽  
Daniel M. Malkamaki ◽  
Devon B. McLennan ◽  
...  
2021 ◽  
Vol 24 (6) ◽  
pp. E821-E828

BACKGROUND: The American Society of Regional Anesthesia currently recommends ceasing antithrombotic medications for all spinal epidural steroid injections, however there is a paucity of data on the true risk of spinal epidurals via various approaches versus the risk of cessation of an agent as it relates to the underlying medical condition. OBJECTIVE: This study evaluated the complication rate of caudal epidural steroid injections in patients who remain on antithrombotic medications. STUDY DESIGN: Retrospective chart review. SETTING: Physiatric Spine Clinic in Orthopedic Specialty Office and Surgical Center. METHODS: A retrospective chart review was performed identifying patients (n = 335) who received a caudal epidural steroid injection (n = 673) from June 2015 through April 2020. Patients were included if they had received the injection while taking an antithrombotic medication. Patients were excluded if they were not taking an antithrombotic. The patient’s age, indication for the injection including magnetic resonance imaging or computed tomography findings, antithrombotic medication, the medical condition requiring an antithrombotic, and any complications following the injection were collected via chart review. RESULTS: Of the 443 injections included in the study, 51 encounters were lost to follow-up. Of the other 392 injections, there were no reported complications, regardless of the patient’s imaging findings, age, the antithrombotic medication used, or the underlying medical condition for which an antithrombotic medication was indicated. LIMITATIONS: This is a retrospective study. Therefore, a prospective study may have yielded fewer encounters lost to follow-up. Patients were not contacted directly after the procedure and chart reviews were utilized to evaluate for complications, which was limited to a patient’s reporting of perceived complications without any imaging. CONCLUSIONS: We conclude that caudal epidural steroid injections can be performed safely in patients while taking antithrombotic medications. Catastrophic events have been observed in patients who have discontinued antithrombotic agents preceding procedures. Thus, discontinuing antithrombotic medications may pose a greater risk than benefit for patients on an antithrombotic medication who have painful lumbar radiculopathy. KEY WORDS: Epidural injection, caudal, antithrombotic, safety, steroids, anticoagulant, antiplatelet, epidural hematoma


2020 ◽  
pp. 25-32
Author(s):  
Calvin Rong Chen

Background: Epidural injections have been used for pain relief since the 1880s. Corticosteroids are antiinflammatory medications that can alleviate pain, but also have harmful systemic adverse effects. Literature regarding methylprednisolone dosage efficacy is limited. Objectives: To determine the lowest effective dose of methylprednisolone in a lumbar epidural steroid injection (LESI) for maximal pain relief without exposing patients to adverse events caused by steroid use. Study Design: Retrospective chart review. Setting: Outpatient interventional pain clinic at an academic center. Methods: Adults (n = 133), aged 18 to 85 years, with low-back pain and radicular symptoms treated with LESI from August 2011 to November 2015. Patients who received prior cervical epidural steroid injections were excluded. Interventions were LESI with methylprednisolone 40 mg, 80 mg, or 120 mg. Main outcome measures showed change in pain score using a numeric pain scale (NPS; 0 = no pain, 10 = excruciating pain), and patient’s self-reported reduction in pain (percentage), pre- and postprocedure. The primary endpoint measurement was 2 weeks postinjection. Adverse effects were recorded. Results: The number of patients who received each dose varied: n = 88 received 120 mg, n = 30 received 80 mg, and n = 13 received 40 mg. The NPS pain scores pre- and postprocedure for 120 mg were 8.89 ± 1.32 and 4.08 ± 3.74, (mean ± standard deviation), respectively; for 80 mg: 9.06 ± 1.00 and 3.75 ± 4.00; and for 40 mg: 9.00 ± 1.00 and 4.00 ± 0.00. Percentage of pain relief for 120 mg, 80 mg, and 40 mg was 57.26%, 50.74%, and 57.26, respectively (P = 0.3347). n = 4 experienced adverse effects, all received 120 mg. Conclusions: All 3 dosage groups had similar efficacy in pain relief, but only patients who received 120 mg experienced adverse effects. This demonstrates that lower dosages can be used for pain relief with less potential harm to the patient. Key words: Methylprednisolone, interlaminar epidural, radiculopathy


Sign in / Sign up

Export Citation Format

Share Document