Poster 3 Voxel-Based Statistical Analysis of Brain Metabolism in Patients With Growth Hormone Deficiency After Traumatic Brain Injury

2012 ◽  
Vol 93 (10) ◽  
pp. e15
Author(s):  
Ki Deok Park ◽  
Jiwon Lee ◽  
Yongbum Park
Brain Injury ◽  
2016 ◽  
Vol 30 (4) ◽  
pp. 407-413 ◽  
Author(s):  
Ki Deok Park ◽  
Oh Kyung Lim ◽  
Chan Jong Yoo ◽  
Yong Wook Kim ◽  
Sihoon Lee ◽  
...  

2009 ◽  
Vol 17 (5) ◽  
pp. 696-702 ◽  
Author(s):  
D. Pavlovic ◽  
S. Pekic ◽  
M. Stojanovic ◽  
V. Zivkovic ◽  
B. Djurovic ◽  
...  

2005 ◽  
Vol 86 (3) ◽  
pp. 463-468 ◽  
Author(s):  
Felipe F. Casanueva ◽  
Alfonso Leal ◽  
Maria Koltowska-Häggström ◽  
Peter Jonsson ◽  
Miklós I. Góth

2019 ◽  
Vol 20 (13) ◽  
pp. 3323 ◽  
Author(s):  
Oratile Kgosidialwa ◽  
Osamah Hakami ◽  
Hafiz Muhammad Zia-Ul-Hussnain ◽  
Amar Agha

Traumatic brain injury (TBI) is fairly common and annually affects millions of people worldwide. Post traumatic hypopituitarism (PTHP) has been increasingly recognized as an important and prevalent clinical entity. Growth hormone deficiency (GHD) is the most common pituitary hormone deficit in long-term survivors of TBI. The pathophysiology of GHD post TBI is thought to be multifactorial including primary and secondary mechanisms. An interplay of ischemia, cytotoxicity, and inflammation post TBI have been suggested, resulting in pituitary hormone deficits. Signs and symptoms of GHD can overlap with those of TBI and may delay rehabilitation/recovery if not recognized and treated. Screening for GHD is recommended in the chronic phase, at least six months to a year after TBI as GH may recover in those with GHD in the acute phase; conversely, it may manifest in those with a previously intact GH axis. Dynamic testing is the standard method to diagnose GHD in this population. GHD is associated with long-term poor medical outcomes. Treatment with recombinant human growth hormone (rhGH) seems to ameliorate some of these features. This review will discuss the frequency and pathophysiology of GHD post TBI, its clinical consequences, and the outcomes of treatment with GH replacement.


2008 ◽  
Vol 152 (4) ◽  
pp. 590-593 ◽  
Author(s):  
Anna McDonald ◽  
Margaretha Lindell ◽  
David B. Dunger ◽  
Carlo L. Acerini

2017 ◽  
Vol 41 (5) ◽  
pp. S35-S36
Author(s):  
Kirstie Lithgow ◽  
Alex Chin ◽  
Chantel Debert ◽  
Gregory Kline

2007 ◽  
Vol 67 (1) ◽  
pp. 177-179
Author(s):  
Nadja Maric ◽  
Sandra Pekic ◽  
Mira Doknic ◽  
Miroslava Jasovic-Gasic ◽  
Vlada Zivkovic ◽  
...  

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