Neopterin levels and left ventricular dysfunction in patients with chronic stable angina pectoris

2009 ◽  
Vol 207 (2) ◽  
pp. 514-518 ◽  
Author(s):  
Rodrigo Estévez-Loureiro ◽  
Alejandro Recio-Mayoral ◽  
Juan A. Sieira-Rodríguez-Moret ◽  
Ernesto Trallero-Araguás ◽  
Juan Carlos Kaski
Keyword(s):  
Angina Pectoris ◽  
Left Ventricular Dysfunction ◽  
Stable Angina ◽  
Ventricular Dysfunction ◽  
Chronic Stable Angina ◽  
Left Ventricular ◽  
Stable Angina Pectoris

scholarly journals Comparison of the efficacy of Ivabradine and Nebivolol as Mono Therapy in the Treatment of Stable Angina Pectoris Patients with Mild Left Ventricular Dysfunction

2019 ◽  
Vol 15 (1) ◽  
pp. 8-11
Author(s):  
Harisul Hoque ◽  
Khurshed Ahmed ◽  
MRM Mandal ◽  
Faisal Ibn Kabir ◽  
Md Abdus Salam ◽  
...  
Keyword(s):  
Heart Rate ◽  
Chest Pain ◽  
Angina Pectoris ◽  
Left Ventricular Dysfunction ◽  
Stable Angina ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Stable Angina Pectoris ◽  
Group A ◽  
Group B

This prospective study aimed to investigate the efficacy of ivabradine and nebivolol in treatment of stable angina pectoris (SAP) patients with mild left ventricular dysfunction. Heart rate decreased (78±6) to (65±5) in Group: A and ( 77± 7) to (70 ± 5) in Group: B. There was no change in Blood pressure reduction in Group:A but significant BP reduction in Nebivolol group. Chest pain was reduced by Ivabradine but in Group : B, chest pain decreased in long term after 6 weeks time. After 6 months’ treatment LVEF for the 15 patients of nebivolol group (50%; Group: A) improved by (48 ± 6.5) to (51 ± 3.2), (p>0.05) and for the 15 patients of Ivabradine group (50%; Group: B) (47 ± 5.4) to (51 ± 2.3), (p>0.05). Ivabradine can be considered as first choice in patient with tachycardia induced angina as this agent for reducing heart rate as well as chest pain. The hypertensive patient with tachycardia may be treated by Nebivolol. Among patients in which effective treatment could not be achieved at maximum nebivolol doses, more effective results were obtained in this study with Ivabradine. University Heart Journal Vol. 15, No. 1, Jan 2019; 8-11

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