scholarly journals Histological and functional renal alterations caused by Bothrops alternatus snake venom: Expression and activity of Na+/K+-ATPase

2011 ◽  
Vol 1810 (9) ◽  
pp. 895-906 ◽  
Author(s):  
Alessandra Linardi ◽  
Thomaz A.A. Rocha e Silva ◽  
Elen H. Miyabara ◽  
Carla F. Franco-Penteado ◽  
Kiara C. Cardoso ◽  
...  
Keyword(s):  
Snake Venom ◽  
Bothrops Alternatus ◽  
Expression And Activity

Binding of acidic PLA2 Ba SPII RP4 from Bothrops alternatus snake venom to integrin αvβ3: An in silico study

Toxicon ◽  
2020 ◽  
Vol 177 ◽  
pp. S52
Author(s):  
Emilio Angelina ◽  
Soledad Bustillo ◽  
Lucrecia Bogado ◽  
María Emilia García Denegri ◽  
Nelida Peruchena ◽  
...  
Keyword(s):  
Snake Venom ◽  
In Silico ◽  
Integrin Αvβ3 ◽  
Bothrops Alternatus ◽  
In Silico Study

scholarly journals Renal kinetics of Bothrops alternatus (Urutu) snake venom in rats

Toxicon ◽  
2010 ◽  
Vol 55 (2-3) ◽  
pp. 470-480 ◽  
Author(s):  
Sueli M. Mello ◽  
Alessandra Linardi ◽  
André L. Rennó ◽  
Christiane A.B. Tarsitano ◽  
Elionai M. Pereira ◽  
...  
Keyword(s):  
Snake Venom ◽  
Bothrops Alternatus ◽  
Kinetics Of

Apoptosis induced by a snake venom metalloproteinase from Bothrops alternatus venom in C2C12 muscle cells

APOPTOSIS ◽  
2017 ◽  
Vol 22 (4) ◽  
pp. 491-501 ◽  
Author(s):  
Soledad Bustillo ◽  
Andrea C. Van de Velde ◽  
Verónica Matzner Perfumo ◽  
Claudia C. Gay ◽  
Laura C. Leiva
Keyword(s):  
Snake Venom ◽  
Muscle Cells ◽  
Bothrops Alternatus ◽  
Snake Venom Metalloproteinase ◽  
C2c12 Muscle Cells

Platelet Aggregation and Antibacterial Effects of an L-Amino Acid Oxidase Purified from Bothrops alternatus Snake Venom.

ChemInform ◽  
2004 ◽  
Vol 35 (36) ◽  
Author(s):  
Rodrigo G. Stabeli ◽  
Silvana Marcussi ◽  
Guilherme B. Carlos ◽  
Rosemeire C. L. R. Pietro ◽  
Heloisa S. Selistre-de-Araujo ◽  
...  
Keyword(s):  
Amino Acid ◽  
Platelet Aggregation ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Antibacterial Effects ◽  
Amino Acid Oxidase ◽  
Bothrops Alternatus

Histological and Ultrastructural Analyses of Muscle Damage Induced by a Myotoxin Isolated from Bothrops alternatus Snake Venom

2013 ◽  
Vol 20 (2) ◽  
pp. 192-199 ◽  
Author(s):  
Carla Cristine Neves Mamede ◽  
Mayara Ribeiro de Queiroz ◽  
Kelly Cortes Fonseca ◽  
Nadia Cristina Gomes de Morais ◽  
Saulo Antonio Gomes Filho ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Snake Venom ◽  
Bothrops Alternatus

Evaluation of pro-inflammatory events induced by Bothrops alternatus snake venom

2018 ◽  
Vol 281 ◽  
pp. 24-31 ◽  
Author(s):  
Silvina Echeverría ◽  
Elbio Leiguez ◽  
Carlos Guijas ◽  
Neide Galvão do Nascimento ◽  
Ofelia Acosta ◽  
...  
Keyword(s):  
Snake Venom ◽  
Bothrops Alternatus

scholarly journals Neuromuscular activity of BaTX, a presynaptic basic PLA2 isolated from Bothrops alternatus snake venom

2009 ◽  
Vol 150 (2) ◽  
pp. 291-297 ◽  
Author(s):  
L.A. Ponce-Soto ◽  
J.C. Barros ◽  
S. Marangoni ◽  
S. Hernandez ◽  
C.A. Dal Belo ◽  
...  
Keyword(s):  
Snake Venom ◽  
Neuromuscular Activity ◽  
Bothrops Alternatus

scholarly journals Cytotoxic Activity Of A New Isoform L-Amino Acid Oxidase (Balt-LAAO-II) From Bothrops alternatus (Urutu) Snake Venom In Human Leukemic HL60 Cells

2020 ◽  
Author(s):  
Maurício Aurelio Gomes Heleno ◽  
João Ernesto de Carvalho ◽  
Alexandre Nowill ◽  
Luis Alberto Ponce-Soto
Keyword(s):  
Amino Acid ◽  
Snake Venom ◽  
Neutral Red ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Hl60 Cells ◽  
Bothrops Alternatus ◽  
Diphenyl Tetrazolium Bromide ◽  
Induced Apoptosis

AbstractIn this work we describe the isolation of a new isoform L-amino acid oxidase (LAAO) referred to as Balt-LAAO-II from Bothrops alternatus snake venom, which was highly purified using a combination of molecular exclusion (Sephadex G-75) and RP-HPLC chromatographics steps. When analyzed by SDS-PAGE, the purified Balt-LAAO-II presented a molecular weight of ∼66 kDa. The N-terminal amino acid sequence and internal peptide sequences showed close structural homology to other snake venom L-amino acid oxidases.This enzyme induces in vitro cytotoxicity on cultured human leukemic HL60 cells. Cells were grown in RPMI medium and were incubated with isoform Balt-LAAO-II (1, 10 and 100 μg/mL) for up to 72 h. All three concentrations of venom markedly decreased the cell viability from 6 h onwards based on the staining with propidium iodide, the reduction of 3-(4,5-dimethylthazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and the uptake of neutral red.Flow cytometry showed that all isoform Balt-LAAO-II and whole venom concentrations induced apoptosis after 2-6 h of incubation. Morphological analysis of cells incubated with isoform Balt-LAAO-II and whole venom showed cell rounding and lysis that increased with the venom concentration and duration of incubation. These results show that isoform Balt-LAAO-II from venom Bothrops alternatus is cytotoxic to cultured HL60 cells and suggest that this damage may involve apoptotic and oxidative stress pathways.

Platelet aggregation and antibacterial effects of an l-amino acid oxidase purified from Bothrops alternatus snake venom

2004 ◽  
Vol 12 (11) ◽  
pp. 2881-2886 ◽  
Author(s):  
Rodrigo G. Stábeli ◽  
Silvana Marcussi ◽  
Guilherme B. Carlos ◽  
Rosemeire C.L.R. Pietro ◽  
Heloı́sa S. Selistre-de-Araújo ◽  
...  
Keyword(s):  
Amino Acid ◽  
Platelet Aggregation ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Antibacterial Effects ◽  
Amino Acid Oxidase ◽  
Bothrops Alternatus

BaltPLA2: A New Phospholipase A2 from Bothrops Alternatus Snake Venom with Antiplatelet Aggregation Activity

2018 ◽  
Vol 25 (10) ◽  
pp. 943-952 ◽  
Author(s):  
Edigar Henrique Vaz Dias ◽  
Tamires dos Santos Paschoal ◽  
Alisson Pereira da Silva ◽  
Déborah Fernanda da Cunha Pereira ◽  
Bruna Barbosa de Sousa Simamoto ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Snake Venom ◽  
Antiplatelet Aggregation ◽  
Bothrops Alternatus ◽  
Aggregation Activity
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