Hepatic lysosomal acid lipase drives the autophagy-lysosomal response and alleviates cholesterol metabolic disorder in ApoE deficient mice

Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe

Biochemical Pharmacology ◽

10.1016/j.bcp.2017.03.010 ◽

2017 ◽

Vol 135 ◽

pp. 116-125 ◽

Cited By ~ 5

Author(s):

Jen-Chieh Chuang ◽

Adam M. Lopez ◽

Stephen D. Turley

Keyword(s):

Cholesterol Synthesis ◽

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Reversal of advanced disease in lysosomal acid lipase deficient mice: A model for lysosomal acid lipase deficiency disease

Molecular Genetics and Metabolism ◽

10.1016/j.ymgme.2014.04.006 ◽

2014 ◽

Vol 112 (3) ◽

pp. 229-241 ◽

Cited By ~ 18

Author(s):

Ying Sun ◽

You-Hai Xu ◽

Hong Du ◽

Brian Quinn ◽

Benjamin Liou ◽

...

Keyword(s):

Advanced Disease ◽

Deficiency Disease ◽

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Lysosomal Acid Lipase Deficiency ◽

Endothelial Rab7 GTPase mediates tumor growth and metastasis in lysosomal acid lipase–deficient mice

Journal of Biological Chemistry ◽

10.1074/jbc.m116.773093 ◽

2017 ◽

Vol 292 (47) ◽

pp. 19198-19208 ◽

Cited By ~ 3

Author(s):

Ting Zhao ◽

Xinchun Ding ◽

Cong Yan ◽

Hong Du

Keyword(s):

Tumor Growth ◽

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Tumor Growth And Metastasis ◽

Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)31157-3 ◽

2001 ◽

Vol 42 (4) ◽

pp. 489-500

Author(s):

Hong Du ◽

Martin Heur ◽

Ming Duanmu ◽

Gregory A. Grabowski ◽

David Y. Hui ◽

...

Keyword(s):

Life Span ◽

Brown Fat ◽

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

PRD125, a Potent and Selective Inhibitor of Sterol O-Acyltransferase 2 Markedly Reduces Hepatic Cholesteryl Ester Accumulation and Improves Liver Function in Lysosomal Acid Lipase-Deficient Mice

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.115.227207 ◽

2015 ◽

Vol 355 (2) ◽

pp. 159-167 ◽

Cited By ~ 6

Author(s):

Adam M. Lopez ◽

Jen-Chieh Chuang ◽

Kenneth S. Posey ◽

Taichi Ohshiro ◽

Hiroshi Tomoda ◽

...

Keyword(s):

Liver Function ◽

Cholesteryl Ester ◽

Selective Inhibitor ◽

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Deficient Mice ◽

Cholesteryl Ester Accumulation

THE FIRST RUSSIA EXPERIENCE WITH THE USE OF ENZYME REPLACEMENT THERAPY WITH SEBELIPASE ALPHA IN A CHILD WITH AN INFANTILE FORM OF LYSOSOMAL ACID LIPASE DEFICIENCY

PEDIATRIA Journal named after G N SPERANSKY ◽

10.24110/0031-403x-2020-99-1-226-232 ◽

2020 ◽

Vol 99 (1) ◽

pp. 226-232

Author(s):

A.N. Surkov ◽

◽

A.O. Anushenko ◽

G.B. Movsisyan ◽

A.S. Potapov ◽

...

Keyword(s):

Enzyme Replacement Therapy ◽

Replacement Therapy ◽

Infantile Form ◽

Acid Lipase ◽

Lysosomal Acid ◽

Enzyme Replacement ◽

Lysosomal Acid Lipase ◽

Orphan designation: Recombinant human lysosomal acid lipase, Treatment of lysosomal acid lipase deficiency

Case Medical Research ◽

10.31525/cmr-2249a9f ◽

2019 ◽

Author(s):

Keyword(s):

Acid Lipase ◽

Lysosomal Acid ◽

Orphan Designation ◽

Lysosomal Acid Lipase ◽

Lysosomal Acid Lipase Deficiency: Could Dyslipidemia Drive the Diagnosis?

Current Pediatric Reviews ◽

10.2174/1573396314666180111144514 ◽

2018 ◽

Vol 13 (4) ◽

pp. 232-242

Author(s):

Ornella Guardamagna ◽

Federica Guaraldi

Keyword(s):

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Living Donor Liver Transplantation for Late-onset Lysosomal acid lipase deficiency

Journal of Clinical and Experimental Hepatology ◽

10.1016/j.jceh.2021.06.022 ◽

2021 ◽

Author(s):

Somashekara HR ◽

Mohan Babu Kasala ◽

Karnan Perumal ◽

Selvakumar Malleeswaran ◽

Rajanikanth V. Patcha ◽

...

Keyword(s):

Liver Transplantation ◽

Living Donor ◽

Living Donor Liver Transplantation ◽

Late Onset ◽

Acid Lipase ◽

Donor Liver ◽

Lysosomal Acid ◽

Donor Liver Transplantation ◽

Lysosomal Acid Lipase ◽

Low levels of Lysosomal Acid Lipase (LAL) activity increases necroinflammation in adult patients with biopsy-proven metabolic associated fatty liver disease

Clinics and Research in Hepatology and Gastroenterology ◽

10.1016/j.clinre.2021.101638 ◽

2021 ◽

Vol 45 (6) ◽

pp. 101638

Author(s):

Rutiane Ullmann Thoen ◽

Larisse Longo ◽

Santiago Cassales Neto ◽

Mário Reis Álvares-da-Silva

Keyword(s):

Liver Disease ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Adult Patients ◽

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Low Levels