Molecular cloning and characterization of a new peptide deformylase from human pathogenic bacterium Helicobacter pylori

2004 ◽  
Vol 319 (4) ◽  
pp. 1292-1298 ◽  
Author(s):  
Cong Han ◽  
Qi Wang ◽  
Lei Dong ◽  
Haifang Sun ◽  
Shuying Peng ◽  
...  
2018 ◽  
Author(s):  
Jerson Alexander Garcia-Zea ◽  
Roberto de la Herrán ◽  
Francisca Robles Rodríguez ◽  
Rafael Navajas-Pérez ◽  
Carmelo Ruiz Rejón

Helicobacter pylori is a human pathogenic bacterium with a high genomic plasticity. Although the functional CRISPR-Cas system has not been found in its genome, CRISPR like loci have been recently identified. In this work, 53 genomes from different geographical areas are analyzed for the search and analysis of variability of this type of structure. We confirm the presence of a locus that was previously described in the VlpC gene in al lgenomes, and we characterize new CRISPR-like loci in other genomic locations. By studying the variability and gene location of these loci, the evolution and the possible roles of these sequences are discussed. Additionally, the usefulness of this type of sequences as a phylogenetic marker has been demonstrated, associating the different strains by geographical area.


2000 ◽  
Vol 174 (1-2) ◽  
pp. 104-110 ◽  
Author(s):  
Guadalupe Oliva ◽  
Irma Romero ◽  
Guadalupe Ayala ◽  
Idanelli Barrios-Jacobo ◽  
Heliodoro Celis

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6221
Author(s):  
Jerson Alexander García-Zea ◽  
Roberto de la Herrán ◽  
Francisca Robles Rodríguez ◽  
Rafael Navajas-Pérez ◽  
Carmelo Ruiz Rejón

Helicobacter pyloriis a human pathogenic bacterium with a high genomic plasticity. Although the functional CRISPR-Cas system has not been found in its genome, CRISPR-like loci have been recently identified. In this work, 53 genomes from different geographical areas are analyzed for the search and analysis of variability of this type of structure. We confirm the presence of a locus that was previously described in the VlpC gene in al lgenomes, and we characterize new CRISPR-like loci in other genomic locations. By studying the variability and gene location of these loci, the evolution and the possible roles of these sequences are discussed. Additionally, the usefulness of this type of sequences as a phylogenetic marker has been demonstrated, associating the different strains by geographical area.


2018 ◽  
Author(s):  
Jerson Alexander Garcia-Zea ◽  
Roberto de la Herrán ◽  
Francisca Robles Rodríguez ◽  
Rafael Navajas-Pérez ◽  
Carmelo Ruiz Rejón

Helicobacter pylori is a human pathogenic bacterium with a high genomic plasticity. Although the functional CRISPR-Cas system has not been found in its genome, CRISPR like loci have been recently identified. In this work, 53 genomes from different geographical areas are analyzed for the search and analysis of variability of this type of structure. We confirm the presence of a locus that was previously described in the VlpC gene in al lgenomes, and we characterize new CRISPR-like loci in other genomic locations. By studying the variability and gene location of these loci, the evolution and the possible roles of these sequences are discussed. Additionally, the usefulness of this type of sequences as a phylogenetic marker has been demonstrated, associating the different strains by geographical area.


1994 ◽  
Vol 92 (3) ◽  
pp. 511-515 ◽  
Author(s):  
Kang Chong ◽  
Li-Ping Wang ◽  
Ke-Hui Tan ◽  
Hua-Liang Huang ◽  
Hou-Guo Liang

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