Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus

Tyrosine Phosphatase ◽

Protein-Tyrosine Phosphatase 1B (PTP1B): A Novel Therapeutic Target for Type 2 Diabetes Mellitus, Obesity and Related States of Insulin Resistance

Current Drug Targets - Immune Endocrine & Metabolic Disorders ◽

10.2174/1568008013341163 ◽

2001 ◽

Vol 1 (3) ◽

pp. 265-275 ◽

Cited By ~ 86

Author(s):

B.J. Goldstein

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Therapeutic Target ◽

Tyrosine Phosphatase ◽

Novel Therapeutic

An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2018.10.024 ◽

2018 ◽

Vol 28 (23-24) ◽

pp. 3712-3720 ◽

Cited By ~ 10

Author(s):

Rosanna Maccari ◽

Antonella Del Corso ◽

Paolo Paoli ◽

Ilenia Adornato ◽

Giulia Lori ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Aldose Reductase ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Dual Inhibitors

Protein Tyrosine Phosphatase N1 Gene Variants Associated with Type 2 Diabetes Mellitus and Its Related Phenotypes in the Korean Population

Genomics & Informatics ◽

10.5808/gi.2008.6.3.099 ◽

2008 ◽

Vol 6 (3) ◽

pp. 99-109

Author(s):

Kyung-Won Hong ◽

Hyun-Seok Jin ◽

Ji-Eun Lim ◽

Ha-Jung Ryu ◽

Youn-Jhin Ahn ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Korean Population ◽

Gene Variants ◽

Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2011.06.009 ◽

2011 ◽

Vol 410 (3) ◽

pp. 377-381 ◽

Cited By ~ 76

Author(s):

Doina Popov

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Obesity Control ◽

Novel Protein

Protein tyrosine phosphatase 1B is not a major susceptibility gene for type 2 diabetes mellitus or obesity among Pima Indians

Diabetologia ◽

10.1007/s00125-007-0611-6 ◽

2007 ◽

Vol 50 (5) ◽

pp. 985-989 ◽

Cited By ~ 13

Author(s):

M. Traurig ◽

R. L. Hanson ◽

S. Kobes ◽

C. Bogardus ◽

L. J. Baier

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Susceptibility Gene ◽

Pima Indians ◽

The role of protein tyrosine phosphatase 1B (PTP1B) in the pathogenesis of type 2 diabetes mellitus and its complications

Journal of Physiology and Biochemistry ◽

10.1007/s13105-021-00860-7 ◽

2022 ◽

Author(s):

Maryam Teimouri ◽

Hossein Hosseini ◽

Zahra ArabSadeghabadi ◽

Reyhaneh Babaei-Khorzoughi ◽

Sattar Gorgani-Firuzjaee ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2′,3,3′-Tetrabromo-4,4′,5,5′-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.8b01106 ◽

2019 ◽

Vol 16 (5) ◽

pp. 1839-1850 ◽

Cited By ~ 3

Author(s):

Chao Li ◽

Jiao Luo ◽

Shuju Guo ◽

Xiaoling Jia ◽

Chuanlong Guo ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Protein Tyrosine Phosphatase Inhibitor

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Phosphatase Inhibitor ◽

Type 2 Diabetes Mellitus and Protein-Tyrosine Phosphatase 1B1

Journal of Diabetes Metabolic Disorders & Control ◽

10.15406/jdmdc.2016.03.00096 ◽

2016 ◽

Vol 3 (8) ◽

Cited By ~ 1

Author(s):

Wei Zou

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Protein-Tyrosine Phosphatase 1B (PTP1B): A Novel Therapeutic Target for Type 2 Diabetes Mellitus, Obesity and Related States of Insulin Resistance

Current Drug Targets - Immune Endocrine & Metabolic Disorders ◽

10.2174/1568005310101030265 ◽

2001 ◽

Vol 1 (3) ◽

pp. 265-275 ◽

Cited By ~ 4

Author(s):

Barry J. Goldstein

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Therapeutic Target ◽

Tyrosine Phosphatase ◽

Novel Therapeutic

Marked impairment of protein tyrosine phosphatase 1B activity in adipose tissue of obese subjects with and without type 2 diabetes mellitus

Journal of Laboratory and Clinical Medicine ◽

10.1016/s0022-2143(99)90115-4 ◽

1999 ◽

Vol 134 (2) ◽

pp. 115-123 ◽

Cited By ~ 49

Author(s):

Anthony Cheung ◽

Jyotirmoy Kusari ◽

David Jansen ◽

Debdutta Bandyopadhyay ◽

Anasua Kusari ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Adipose Tissue ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Obese Subjects