The role of protein tyrosine phosphatase 1B (PTP1B) in the pathogenesis of type 2 diabetes mellitus and its complications

Tyrosine Phosphatase ◽

An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2018.10.024 ◽

2018 ◽

Vol 28 (23-24) ◽

pp. 3712-3720 ◽

Cited By ~ 10

Author(s):

Rosanna Maccari ◽

Antonella Del Corso ◽

Paolo Paoli ◽

Ilenia Adornato ◽

Giulia Lori ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Aldose Reductase ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Dual Inhibitors

Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2011.06.009 ◽

2011 ◽

Vol 410 (3) ◽

pp. 377-381 ◽

Cited By ~ 76

Author(s):

Doina Popov

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Obesity Control ◽

Novel Protein

Protein tyrosine phosphatase 1B is not a major susceptibility gene for type 2 diabetes mellitus or obesity among Pima Indians

Diabetologia ◽

10.1007/s00125-007-0611-6 ◽

2007 ◽

Vol 50 (5) ◽

pp. 985-989 ◽

Cited By ~ 13

Author(s):

M. Traurig ◽

R. L. Hanson ◽

S. Kobes ◽

C. Bogardus ◽

L. J. Baier

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Susceptibility Gene ◽

Pima Indians ◽

Marked impairment of protein tyrosine phosphatase 1B activity in adipose tissue of obese subjects with and without type 2 diabetes mellitus

Journal of Laboratory and Clinical Medicine ◽

10.1016/s0022-2143(99)90115-4 ◽

1999 ◽

Vol 134 (2) ◽

pp. 115-123 ◽

Cited By ~ 49

Author(s):

Anthony Cheung ◽

Jyotirmoy Kusari ◽

David Jansen ◽

Debdutta Bandyopadhyay ◽

Anasua Kusari ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Adipose Tissue ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Obese Subjects

Protein-Tyrosine Phosphatase 1B (PTP1B): A Novel Therapeutic Target for Type 2 Diabetes Mellitus, Obesity and Related States of Insulin Resistance

Current Drug Targets - Immune Endocrine & Metabolic Disorders ◽

10.2174/1568008013341163 ◽

2001 ◽

Vol 1 (3) ◽

pp. 265-275 ◽

Cited By ~ 86

Author(s):

B.J. Goldstein

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Therapeutic Target ◽

Tyrosine Phosphatase ◽

Novel Therapeutic

Protein Tyrosine Phosphatase N1 Gene Variants Associated with Type 2 Diabetes Mellitus and Its Related Phenotypes in the Korean Population

Genomics & Informatics ◽

10.5808/gi.2008.6.3.099 ◽

2008 ◽

Vol 6 (3) ◽

pp. 99-109

Author(s):

Kyung-Won Hong ◽

Hyun-Seok Jin ◽

Ji-Eun Lim ◽

Ha-Jung Ryu ◽

Youn-Jhin Ahn ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Korean Population ◽

Gene Variants ◽

Pharmacological Inhibition of Protein Tyrosine Phosphatase 1B: A Promising Strategy for the Treatment of Obesity and Type 2 Diabetes Mellitus

Current Medicinal Chemistry ◽

10.2174/0929867311320210001 ◽

2013 ◽

Vol 20 (21) ◽

pp. 2609-2625 ◽

Cited By ~ 53

Author(s):

E. Panzhinskiy ◽

J. Ren ◽

S. Nair

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Pharmacological Inhibition ◽

Promising Strategy ◽

Treatment Of Obesity

Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus

Best Practice & Research Clinical Endocrinology & Metabolism ◽

10.1016/j.beem.2007.08.004 ◽

2007 ◽

Vol 21 (4) ◽

pp. 621-640 ◽

Cited By ~ 145

Author(s):

Shlomit Koren ◽

I. George Fantus

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2′,3,3′-Tetrabromo-4,4′,5,5′-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.8b01106 ◽

2019 ◽

Vol 16 (5) ◽

pp. 1839-1850 ◽

Cited By ~ 3

Author(s):

Chao Li ◽

Jiao Luo ◽

Shuju Guo ◽

Xiaoling Jia ◽

Chuanlong Guo ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Protein Tyrosine Phosphatase Inhibitor

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Phosphatase Inhibitor ◽

In SilicoStructure-Based Design of a Potent and Selective Small Peptide Inhibitor of Protein Tyrosine Phosphatase 1B, A Novel Therapeutic Target for Obesity and Type 2 Diabetes Mellitus: A Computer Modeling Approach

Journal of Biomolecular Structure and Dynamics ◽

10.1080/07391102.2006.10531233 ◽

2006 ◽

Vol 23 (4) ◽

pp. 377-384 ◽

Cited By ~ 14

Author(s):

Gita Subba Rao ◽

Manoj V. Ramachandran ◽

J. S. Bajaj

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Tyrosine Phosphatase ◽

Peptide Inhibitor ◽

Small Peptide ◽

Novel Therapeutic