Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors

2012 ◽  
Vol 20 (12) ◽  
pp. 3865-3872 ◽  
Author(s):  
Peng Guan ◽  
Feng’e Sun ◽  
Xuben Hou ◽  
Feng Wang ◽  
Fan Yi ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Hydroxamic Acid ◽  
Histone Deacetylase Inhibitors ◽  
Design Synthesis ◽  
Hydroxamic Acid Derivatives

Design, synthesis, and evaluation of cyclic amide/imide-bearing hydroxamic acid derivatives as class-selective histone deacetylase (HDAC) inhibitors

2006 ◽  
Vol 14 (22) ◽  
pp. 7625-7651 ◽  
Author(s):  
Chihiro Shinji ◽  
Satoko Maeda ◽  
Keisuke Imai ◽  
Minoru Yoshida ◽  
Yuichi Hashimoto ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Hydroxamic Acid ◽  
Hdac Inhibitors ◽  
Design Synthesis ◽  
Cyclic Amide ◽  
Hydroxamic Acid Derivatives

Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors

2007 ◽  
Vol 17 (17) ◽  
pp. 4895-4900 ◽  
Author(s):  
Shoukou Lee ◽  
Chihiro Shinji ◽  
Kiyoshi Ogura ◽  
Motomu Shimizu ◽  
Satoko Maeda ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Hydroxamic Acid ◽  
Hdac Inhibitors ◽  
Design Synthesis ◽  
Hydroxamic Acid Derivatives
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