Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113893 ◽

2022 ◽

Vol 227 ◽

pp. 113893

Author(s):

Bei-Er Jiang ◽

Jiaxin Hu ◽

Hao Liu ◽

Zhitao Liu ◽

Yu Wen ◽

...

Keyword(s):

Histone Deacetylase ◽

Hydroxamic Acid ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Hydroxamic Acid Derivatives

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Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.08.030 ◽

2014 ◽

Vol 22 (21) ◽

pp. 6146-6155 ◽

Author(s):

Wei Yang ◽

Lixuan Li ◽

Xun Ji ◽

Xiaowei Wu ◽

Mingbo Su ◽

...

Keyword(s):

Histone Deacetylase ◽

Hydroxamic Acid ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Hydroxamic Acid Derivatives

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Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation

ACS Omega ◽

10.1021/acsomega.0c05870 ◽

2021 ◽

Vol 6 (7) ◽

pp. 4907-4920

Author(s):

Duong T. Anh ◽

Pham-The Hai ◽

Le D. Huy ◽

Hoang B. Ngoc ◽

Trinh T. M. Ngoc ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as Aminopeptidase N (APN) Inhibitors

ChemMedChem ◽

10.1002/cmdc.201700690 ◽

2018 ◽

Vol 13 (5) ◽

pp. 431-436 ◽

Author(s):

Jiangying Cao ◽

Jie Zang ◽

Chunhua Ma ◽

Xiaoguang Li ◽

Jinning Hou ◽

...

Keyword(s):

Hydroxamic Acid ◽

Biological Evaluation ◽

Aminopeptidase N ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Hydroxamic Acid Derivatives

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Design, Synthesis, and Biological Evaluation of Vanillin Hydroxamic Acid Derivatives as Novel Peptide Deformylase Inhibitors

Current Computer - Aided Drug Design ◽

10.2174/1573409913666170613074601 ◽

2018 ◽

Vol 14 (1) ◽

pp. 95-101 ◽

Author(s):

Jian Gao ◽

Shengzhi Qiu ◽

Li Liang ◽

Zhixiang Hao ◽

Qianqian Zhou ◽

...

Keyword(s):

Hydroxamic Acid ◽

Biological Evaluation ◽

Peptide Deformylase ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Hydroxamic Acid Derivatives

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Design, synthesis and biological evaluation of novel hydroxamic acid based histone deacetylase 6 selective inhibitors bearing phenylpyrazol scaffold as surface recognition motif

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.08.029 ◽

2018 ◽

Vol 26 (8) ◽

pp. 1418-1425 ◽

Author(s):

Jinyu Yang ◽

Gaoliang Cheng ◽

Qihao Xu ◽

Shenglin Luan ◽

Shuxiang Wang ◽

...

Keyword(s):

Histone Deacetylase ◽

Hydroxamic Acid ◽

Biological Evaluation ◽

Histone Deacetylase 6 ◽

Selective Inhibitors ◽

Design Synthesis ◽

Recognition Motif ◽

Surface Recognition ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of novel 2,4-thiazolidinedione derivatives as histone deacetylase inhibitors targeting liver cancer cell line

Medicinal Chemistry Research ◽

10.1007/s00044-011-9623-3 ◽

2011 ◽

Vol 21 (7) ◽

pp. 1156-1165 ◽

Author(s):

Rhea Mohan ◽

Ajit K. Sharma ◽

Sanjay Gupta ◽

C. S. Ramaa

Keyword(s):

Liver Cancer ◽

Cell Line ◽

Histone Deacetylase ◽

Cancer Cell ◽

Histone Deacetylase Inhibitors ◽

Cancer Cell Line ◽

Biological Evaluation ◽

Liver Cancer Cell ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.04.032 ◽

2012 ◽

Vol 20 (12) ◽

pp. 3865-3872 ◽

Author(s):

Peng Guan ◽

Feng’e Sun ◽

Xuben Hou ◽

Feng Wang ◽

Fan Yi ◽

...

Keyword(s):

Histone Deacetylase ◽

Hydroxamic Acid ◽

Histone Deacetylase Inhibitors ◽

Design Synthesis ◽

Hydroxamic Acid Derivatives

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Design, synthesis and biological evaluation of 4-piperidin-4-yl-triazole derivatives as novel histone deacetylase inhibitors

BioScience Trends ◽

10.5582/bst.2019.01055 ◽

2019 ◽

Vol 13 (2) ◽

pp. 197-203 ◽

Author(s):

He Miao ◽

Jianjun Gao ◽

Zishuo Mou ◽

Baolei Wang ◽

Li Zhang ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Triazole Derivatives ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.104023 ◽

2020 ◽

Vol 101 ◽

pp. 104023 ◽

Author(s):

Jiaoli Ding ◽

Jing Liu ◽

Zhipeng Zhang ◽

Jie Guo ◽

Maojun Cheng ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Anticancer Activities ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.08.041 ◽

2018 ◽

Vol 143 ◽

pp. 320-333 ◽

Author(s):

Rui Xie ◽

Yan Li ◽

Pingwah Tang ◽

Qipeng Yuan

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Antitumor Agents ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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