Novel naphthyloxy derivatives – Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation

Dorota Łażewska; Maria Kaleta; Stefanie Hagenow; Szczepan Mogilski; Gniewomir Latacz; Tadeusz Karcz; Annamaria Lubelska; Ewelina Honkisz; Jadwiga Handzlik; David Reiner; Grzegorz Satała; Barbara Filipek; Holger Stark; Katarzyna Kieć-Kononowicz

doi:10.1016/j.bmc.2018.04.023

Novel naphthyloxy derivatives – Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2018.04.023 ◽

2018 ◽

Vol 26 (9) ◽

pp. 2573-2585 ◽

Cited By ~ 10

Author(s):

Dorota Łażewska ◽

Maria Kaleta ◽

Stefanie Hagenow ◽

Szczepan Mogilski ◽

Gniewomir Latacz ◽

...

Keyword(s):

Receptor Ligands ◽

Histamine H3 Receptor ◽

Pharmacological Evaluation ◽

H3 Receptor ◽

Histamine H3

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Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H3 receptor ligands

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103071 ◽

2019 ◽

Vol 91 ◽

pp. 103071 ◽

Cited By ~ 4

Author(s):

Katarzyna Szczepańska ◽

Tadeusz Karcz ◽

Agata Siwek ◽

Kamil J. Kuder ◽

Gniewomir Latacz ◽

...

Keyword(s):

Receptor Ligands ◽

Histamine H3 Receptor ◽

Structural Modifications ◽

Pharmacological Evaluation ◽

Piperazine Derivatives ◽

H3 Receptor ◽

Histamine H3

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Search for multifunctional agents against Alzheimer’s disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103084 ◽

2019 ◽

Vol 90 ◽

pp. 103084 ◽

Cited By ~ 1

Author(s):

Jakub Jończyk ◽

Krzysztof Lodarski ◽

Marek Staszewski ◽

Justyna Godyń ◽

Paula Zaręba ◽

...

Keyword(s):

Computational Studies ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

Pharmacological Evaluation ◽

Piperazine Derivatives ◽

H3 Receptor ◽

Multifunctional Agents ◽

Histamine H3

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Diether (substituted) piperidine derivatives as novel, histamine H3 receptor ligands

Inflammation Research ◽

10.1007/s00011-009-2002-6 ◽

2009 ◽

Vol 58 (S1) ◽

pp. 47-48

Author(s):

K. J. Kuder ◽

X. Ligneau ◽

J.-C. Camelin ◽

D. Łażewska ◽

J.-C. Schwartz ◽

...

Keyword(s):

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Metabolic benefits of novel histamine H3 receptor ligands in the model of excessive eating: The importance of intrinsic activity and pharmacokinetic properties

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2021.111952 ◽

2021 ◽

Vol 142 ◽

pp. 111952

Author(s):

Kamil Mika ◽

Małgorzata Szafarz ◽

Marek Bednarski ◽

Kamil Kuder ◽

Katarzyna Szczepańska ◽

...

Keyword(s):

Intrinsic Activity ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Pharmacokinetic Properties ◽

Histamine H3

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Corrigendum to “Waking selective neurons in the posterior hypothalamus and their response to histamine H3-receptor ligands: an electrophsiological study in freely moving cats” [Behav. Brain Res. 144 (2003) 227–241]

Behavioural Brain Research ◽

10.1016/j.bbr.2004.02.004 ◽

2004 ◽

Vol 152 (1) ◽

pp. 163

Author(s):

G. Vanni-Mercier ◽

S. Gigout ◽

G. Debilly ◽

J.S. Lin

Keyword(s):

Posterior Hypothalamus ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Freely Moving ◽

Freely Moving Cats ◽

Histamine H3

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Corrigendum to “Search for new multi-target compounds against Alzheimer’s disease among histamine H3 receptor ligands” [Eur. J. Med. Chem. 185 (2020) 111785]

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112611 ◽

2020 ◽

Vol 205 ◽

pp. 112611

Author(s):

Marek Bajda ◽

Dorota Łażewska ◽

Justyna Godyń ◽

Paula Zaręba ◽

Kamil Kuder ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Drug-likeness approach of 2-aminopyrimidines as histamine H3 receptor ligands

Drug Design Development and Therapy ◽

10.2147/dddt.s66179 ◽

2014 ◽

pp. 1499 ◽

Cited By ~ 6

Author(s):

Bassem Shaban Sadek ◽

Annemarie Schreeb ◽

Johannes Stephan Schwed ◽

Lilia Weizel ◽

Holger Stark

Keyword(s):

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Novel and highly potent histamine H3 receptor ligands. Part 3: An alcohol function to improve the pharmacokinetic profile

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.02.118 ◽

2013 ◽

Vol 23 (9) ◽

pp. 2548-2554 ◽

Cited By ~ 3

Author(s):

Olivier Labeeuw ◽

Nicolas Levoin ◽

Olivia Poupardin-Olivier ◽

Thierry Calmels ◽

Xavier Ligneau ◽

...

Keyword(s):

Pharmacokinetic Profile ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer’s disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112743 ◽

2020 ◽

Vol 207 ◽

pp. 112743

Author(s):

Dorota Łażewska ◽

Marek Bajda ◽

Maria Kaleta ◽

Paula Zaręba ◽

Agata Doroz-Płonka ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Rational Design ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Search for new multi-target compounds against Alzheimer’s disease among histamine H3 receptor ligands

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111785 ◽

2020 ◽

Vol 185 ◽

pp. 111785 ◽

Cited By ~ 9

Author(s):

Marek Bajda ◽

Dorota Łażewska ◽

Justyna Godyń ◽

Paula Zaręba ◽

Kamil Kuder ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

Download Full-text