A minimally-masked inactive prodrug of panobinostat that is bioorthogonally activated by gold chemistry

2021 ◽  
pp. 116217
Author(s):  
Belén Rubio-Ruiz ◽  
Ana M. Pérez-López ◽  
Víctor Sebastián ◽  
Asier Unciti-Broceta
Keyword(s):  
2005 ◽  
Vol 311 (1-2) ◽  
pp. 151-161 ◽  
Author(s):  
Hubert Schmidbaur ◽  
Stephanie Cronje ◽  
Bratislav Djordjevic ◽  
Oliver Schuster
Keyword(s):  

1977 ◽  
Vol 8 (12) ◽  
pp. no-no
Author(s):  
H. SCHMIDBAUR
Keyword(s):  

2011 ◽  
Vol 64 (5) ◽  
pp. 658
Author(s):  
Guozhen Liu

This paper reports the strategy of electrochemically reductive adsorption of aryldiazonium salts on electrodes for designing stable sensing interface. The diazonium salt chemistry can serve as an alternative system to alkanethiol-gold chemistry for the modification of electrode surfaces for biosensor applications.


2018 ◽  
Vol 54 (81) ◽  
pp. 11447-11450 ◽  
Author(s):  
Julio Fernandez-Cestau ◽  
Luca Rocchigiani ◽  
Anna Pintus ◽  
Raquel J. Rama ◽  
Peter H. M. Budzelaar ◽  
...  
Keyword(s):  

The reaction of gold hydrides with isocyanides leads to η1-iminoformyl complexes, the first example of an isocyanide insertion in gold chemistry. Key intermediates are gold(ii) isocyanide adducts.


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