Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase

2006 ◽  
Vol 16 (11) ◽  
pp. 2915-2919 ◽  
Author(s):  
Jun Chen ◽  
Jun Liu ◽  
Luyong Zhang ◽  
Guanzhong Wu ◽  
Weiyi Hua ◽  
...  
Keyword(s):  
Oleanolic Acid ◽  
Glycogen Phosphorylase ◽  
Biological Evaluation ◽  
Pentacyclic Triterpenes ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of novel oleanolic acid analogues as potential α-glucosidase inhibitors

2019 ◽  
Vol 164 ◽  
pp. 706-716 ◽  
Author(s):  
Ying-Ying Zhong ◽  
Hui-Sheng Chen ◽  
Pan-Pan Wu ◽  
Bing-Jie Zhang ◽  
Yang Yang ◽  
...  
Keyword(s):  
Oleanolic Acid ◽  
Biological Evaluation ◽  
Glucosidase Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of oleanolic acid derivative–chalcone conjugates as α-glucosidase inhibitors

RSC Advances ◽  
2014 ◽  
Vol 4 (21) ◽  
pp. 10862-10874 ◽  
Author(s):  
Chu Tang ◽  
Linhui Zhu ◽  
Yu Chen ◽  
Rui Qin ◽  
ZhiNan Mei ◽  
...  
Keyword(s):  
Acid Derivative ◽  
Oleanolic Acid ◽  
Biological Evaluation ◽  
Glucosidase Inhibitors ◽  
Inhibitory Activities ◽  
Synthesis And Biological Evaluation ◽  
Oleanolic Acid Derivative

Series of oleanolic acid derivative–chalcone conjugates were designed, synthesized and their α-glucosidase inhibitory activities were investigatedin vitro.

Synthesis and biological evaluation of oleanolic acid derivatives as antitumor agents

2012 ◽  
Vol 14 (4) ◽  
pp. 355-363 ◽  
Author(s):  
Lei Chen ◽  
Jian-Bo Wu ◽  
Fan Lei ◽  
Shan Qian ◽  
Li Hai ◽  
...  
Keyword(s):  
Oleanolic Acid ◽  
Antitumor Agents ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

A library of 1,2,3-triazole-substituted oleanolic acid derivatives as anticancer agents: design, synthesis, and biological evaluation

2015 ◽  
Vol 13 (5) ◽  
pp. 1507-1514 ◽  
Author(s):  
Gaofei Wei ◽  
Weijing Luan ◽  
Shuai Wang ◽  
Shanshan Cui ◽  
Fengran Li ◽  
...  
Keyword(s):  
Oleanolic Acid ◽  
Anticancer Agents ◽  
Cycloaddition Reaction ◽  
Biological Evaluation ◽  
Dipolar Cycloaddition ◽  
Design Synthesis ◽  
Triazole Derivatives ◽  
Synthesis And Biological Evaluation

A series of novel oleanolic acid coupled 1,2,3-triazole derivatives have been designed and synthesized by employing a Cu(i) catalyzed Huisgen 1,3-dipolar cycloaddition reaction.

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