Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agents

2012 ◽  
Vol 22 (24) ◽  
pp. 7659-7661 ◽  
Author(s):  
Ying-Qian Liu ◽  
Wei Dai ◽  
Chih-Ya Wang ◽  
Susan L. Morris-Natschke ◽  
Xing-Wen Zhou ◽  
...  
Keyword(s):  
Cytotoxic Agents ◽  
One Pot ◽  
One Pot Synthesis

Ultrasound assisted one-pot synthesis of 1,2-diaryl azaindoles via Pd/C-Cu catalysis: Identification of potential cytotoxic agents

2019 ◽  
Vol 60 (52) ◽  
pp. 151326
Author(s):  
Rapolu Venkateshwarlu ◽  
Shambhu Nath Singh ◽  
Vidavalur Siddaiah ◽  
Hindupur Ramamohan ◽  
Rambabu Dandela ◽  
...  
Keyword(s):  
Cytotoxic Agents ◽  
One Pot ◽  
One Pot Synthesis ◽  
Ultrasound Assisted

Pd/C-catalyzed Synthesis of 4-biaryl Substituted 2-amino benzo[h] chromene Derivatives as Potential Cytotoxic Agents

2018 ◽  
Vol 15 (2) ◽  
pp. 160-168 ◽  
Author(s):  
Chekuri Sharmila Rani ◽  
Meda Haritha ◽  
Mandava V. Basaveswara Rao ◽  
Manojit Pal
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Ultrasound Irradiation ◽  
Cancer Cell Lines ◽  
Cytotoxic Agents ◽  
One Pot ◽  
Design Synthesis ◽  
One Pot Synthesis ◽  
Cancerous Cell ◽  
The One

Background: We report the design, synthesis and evaluation of a series of 4-biaryl substituted 2-amino benzo[h]chromene derivatives as potential cytotoxic agents. Methods: The one-pot synthesis of this class of compounds was carried out under ultrasound irradiation using an MCR involving Pd/C-catalyzed Suzuki-Miyaura coupling as a key step. Result and Conclusion: Several of these compounds showed promising cytotoxicities when tested against cancer cell lines but no or little effects on non-cancerous cell lines.

Assembly of Quinoline, Triazole and Oxime Ether in a Single Molecular Entity: A Greener and One-pot Synthesis of Novel Oximes as Potential Cytotoxic Agents

2016 ◽  
Vol 13 (3) ◽  
pp. 210-219 ◽  
Author(s):  
Koduru Sri Shanthi Praveena ◽  
Edupuganti Veera Venkat Shivaji Ramarao ◽  
Yedla Poornachandra ◽  
Chityal Ganesh Kumar ◽  
Nallapati Suresh Babu ◽  
...  
Keyword(s):  
Cytotoxic Agents ◽  
Molecular Entity ◽  
Oxime Ether ◽  
One Pot ◽  
One Pot Synthesis

One-pot synthesis and evaluation of novel 3-aryl-6-ethoxycarbonyl-4-hydroxy-2H-pyran-2-one as a potent cytotoxic agent

RSC Advances ◽  
2014 ◽  
Vol 4 (100) ◽  
pp. 56870-56875 ◽  
Author(s):  
Ganesh Raosaheb Dhage ◽  
Shankar Ramchandra Thopate ◽  
Shefali Nishikant Ramteke ◽  
Prasad Padmakar Kulkarni
Keyword(s):  
Cytotoxic Agents ◽  
Cytotoxic Agent ◽  
One Pot ◽  
Open Chain ◽  
One Pot Synthesis

A series of new open chain analogs of Phelligridin J were synthesized and these compounds were found to be highly potent cytotoxic agents.

One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
Bronsted Acids ◽  
One Pot ◽  
Benzyl Alcohols ◽  
Iodonium Salts ◽  
Efficient Approach ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

Facile and Convenient Ag/Cd/Cu Nanoparticle Catalysed One-pot Synthesis of Xanthenes

2017 ◽  
Vol 7 (12) ◽  
pp. 1192-1195
Author(s):  
Y. I. Shaikh ◽  
G. M. Nazeruddin ◽  
Khursheed Ahmed
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Cu Nanoparticle
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