Developing potential Helicobacter pylori urease inhibitors from novel oxoindoline derivatives: Synthesis, biological evaluation and in silico study

2018 ◽  
Vol 28 (19) ◽  
pp. 3182-3186 ◽  
Author(s):  
Yu-Shun Yang ◽  
Mi-Mi Su ◽  
Xu-Ping Zhang ◽  
Qi-Xing Liu ◽  
Zhen-Xiang He ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
In Silico ◽  
Biological Evaluation ◽  
Urease Inhibitors ◽  
In Silico Study

Imino‐2H‐chromene based derivatives as potential anti‐Alzheimer’s agents: Design, synthesis, biological evaluation and in silico study

2021 ◽  
Author(s):  
Mahshid Attarroshan ◽  
Omidreza Firuzi ◽  
Aida Iraji ◽  
Shahrzad Sharifi ◽  
Marjan Tavakkoli ◽  
...  
Keyword(s):  
In Silico ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
In Silico Study

Synthesis, biological evaluation and in silico study of bis-thiourea derivatives as anticancer, antimalarial and antimicrobial agents

2017 ◽  
Vol 26 (12) ◽  
pp. 3136-3148 ◽  
Author(s):  
Ratchanok Pingaew ◽  
Nujarin Sinthupoom ◽  
Prasit Mandi ◽  
Veda Prachayasittikul ◽  
Rungrot Cherdtrakulkiat ◽  
...  
Keyword(s):  
In Silico ◽  
Antimicrobial Agents ◽  
Biological Evaluation ◽  
Thiourea Derivatives ◽  
In Silico Study

3-Arylpropionylhydroxamic acid derivatives as Helicobacter pylori urease inhibitors: Synthesis, molecular docking and biological evaluation

2016 ◽  
Vol 24 (19) ◽  
pp. 4519-4527 ◽  
Author(s):  
Wei-Kang Shi ◽  
Rui-Cheng Deng ◽  
Peng-Fei Wang ◽  
Qin-Qin Yue ◽  
Qi Liu ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Molecular Docking ◽  
Biological Evaluation ◽  
Urease Inhibitors

Semicarbazone derivatives as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation

2018 ◽  
Vol 79 ◽  
pp. 19-26 ◽  
Author(s):  
Syeda Uroos Qazi ◽  
Shafiq Ur Rahman ◽  
Asia Naz Awan ◽  
Mariya al-Rashida ◽  
Rima D. Alharthy ◽  
...  
Keyword(s):  
Molecular Docking ◽  
In Silico ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Urease Inhibitors ◽  
Molecular Docking Studies

Biological evaluation and molecular docking of baicalin and scutellarin as Helicobacter pylori urease inhibitors

2015 ◽  
Vol 162 ◽  
pp. 69-78 ◽  
Author(s):  
Xiao-Dan Yu ◽  
Rong-Bo Zheng ◽  
Jian-Hui Xie ◽  
Ji-Yan Su ◽  
Xiao-Qi Huang ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Molecular Docking ◽  
Biological Evaluation ◽  
Urease Inhibitors

Preparation and biological evaluation of 99mTc N-histamine as a model for brain imaging: in silico study and preclinical evaluation

2018 ◽  
Vol 106 (3) ◽  
pp. 229-238 ◽  
Author(s):  
M. H. Sanad ◽  
Alhussein A. Ibrahim
Keyword(s):  
Reaction Time ◽  
Brain Imaging ◽  
In Silico ◽  
Radiochemical Purity ◽  
Biological Evaluation ◽  
Preclinical Evaluation ◽  
Biodistribution Studies ◽  
In Silico Study ◽  
Substrate Ph

AbstractIn the present work, [99mTc]N-histamine has been labeled using [99mTc≡N]2+core. Factors such as, amount of substrate, pH, reaction temperature,in vitrostability and reaction time, have been systematically studied to optimize high radiochemical purity (>99±0.3). Biodistribution studies indicate the suitability of [99mTc]N-histamine as a novel tracer to image brain. The complex of [99mTc]N-histamine may be considered a highly selective radiotracer for brain imaging.

scholarly journals Design, in-silico study and biological evaluation of newly synthesized 3-chlorobenzofuran congeners as antitubercular agents

2021 ◽  
Vol 14 (4) ◽  
pp. 103034
Author(s):  
Mohammad Mustaqeem Abdullah ◽  
Nasir A. Siddiqui ◽  
Ramzi A. Mothana ◽  
Fahd A. Nasr ◽  
Adnan J. Al-Rehaily ◽  
...  
Keyword(s):  
In Silico ◽  
Biological Evaluation ◽  
Antitubercular Agents ◽  
In Silico Study
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