scholarly journals NIGMS PSI:Biology Initiative -- High-Throughput-Enabled Structural Biology

2010 ◽  
Vol 98 (3) ◽  
pp. 250a
Author(s):  
Peter C. Preusch ◽  
Ravi Basavappa ◽  
Jean Chin ◽  
Charles Edmonds ◽  
Ward Smith ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput

scholarly journals NIGMS PSI:Biology Initiative ‐ Enabling High‐Throughput Structural Biology and Structural Genomics

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Peter C. Preusch ◽  
Ravi Basavappa ◽  
Jean Chin ◽  
Charles Edmonds ◽  
Paula Flicker ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput ◽  
Structural Genomics

scholarly journals Automated cryo-lamella preparation for high-throughput in-situ structural biology

2020 ◽  
Vol 210 (2) ◽  
pp. 107488 ◽  
Author(s):  
Genevieve Buckley ◽  
Gediminas Gervinskas ◽  
Cyntia Taveneau ◽  
Hariprasad Venugopal ◽  
James C. Whisstock ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput

eResearch Solutions for High Throughput Structural Biology

2007 ◽  
Author(s):  
Noel Faux ◽  
Anthony Beitz ◽  
Mark Bate ◽  
Abdullah A. Amin ◽  
Ian Atkinson ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput

scholarly journals Three Essential Resources to Improve Differential Scanning Fluorimetry (DSF) Experiments

2020 ◽  
Author(s):  
Taia Wu ◽  
Joshua Yu ◽  
Zachary Gale-Day ◽  
Amanda Woo ◽  
Arundhati Suresh ◽  
...  
Keyword(s):  
Data Analysis ◽  
Structural Biology ◽  
High Throughput ◽  
Rapid Determination ◽  
Online Data ◽  
Widespread Application ◽  
Chemical Screening ◽  
Differential Scanning Fluorimetry ◽  
Laboratory Tool

AbstractDifferential Scanning Fluorimetry (DSF) is a method that enables rapid determination of a protein’s apparent melting temperature (Tma). Owing to its high throughput, DSF has found widespread application in fields ranging from structural biology to chemical screening. Yet DSF has developed two opposing reputations: one as an indispensable laboratory tool to probe protein stability, another as a frustrating platform that often fails. Here, we aim to reconcile these disparate reputations and help users perform more successful DSF experiments with three resources: an updated, interactive theoretical framework, practical tips, and online data analysis. We anticipate that these resources, made available online at DSFworld (https://gestwickilab.shinyapps.io/dsfworld/), will broaden the utility of DSF.

Structural Proteomics:  Toward High-Throughput Structural Biology as a Tool in Functional Genomics

2003 ◽  
Vol 36 (3) ◽  
pp. 183-189 ◽  
Author(s):  
Adelinda Yee ◽  
Keith Pardee ◽  
Dinesh Christendat ◽  
Alexei Savchenko ◽  
Aled M. Edwards ◽  
...  
Keyword(s):  
Functional Genomics ◽  
Structural Biology ◽  
High Throughput ◽  
Structural Proteomics

scholarly journals APSY-NMR for protein backbone assignment in high-throughput structural biology

2014 ◽  
Vol 61 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Samit Kumar Dutta ◽  
Pedro Serrano ◽  
Andrew Proudfoot ◽  
Michael Geralt ◽  
Bill Pedrini ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput ◽  
Backbone Assignment ◽  
Protein Backbone ◽  
Protein Backbone Assignment
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