Structural characterization and anti-inflammatory activity of a linear β-d-glucan isolated from Pleurotus sajor-caju

2014 ◽  
Vol 113 ◽  
pp. 588-596 ◽  
Author(s):  
Marcia L.L. Silveira ◽  
Fhernanda R. Smiderle ◽  
Carla Porto Moraes ◽  
Débora G. Borato ◽  
Cristiane H. Baggio ◽  
...  
2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Mala Nath ◽  
Hitendra Singh ◽  
George Eng ◽  
Xueqing Song

Reaction(s) of 5′-guanosine monophosphate (5′GMP) with di- and triorganotin(IV) chloride(s) led to formation of organotin(IV) derivatives of general formulae, [R2Sn(5′-GMP)·H2O]n and [(R′3Sn)2(5′-GMP)·H2O]n, where R = Me, n-Bu, and Ph; R′ = Me, i-Pr, n-Bu, and Ph; (5′-GMP)2− = 5′-guanosine monophosphate. An attempt has been made to prove the structures of the resulting derivatives on the basis of FT-IR, multinuclear 1H, 13C, and 119Sn NMR and 119Sn Mössbauer spectroscopic studies. These investigations suggest that both di- and triorganotin(IV)-5′-guanosine monophosphates are polymeric in which (5′-GMP)2− is bonded through phosphate group resulting in a distorted trigonal bipyramidal geometry around tin. The ribose conformation in all of the derivatives is C3′-endo, except diphenyltin(IV) and tri-i-propyltin(IV) derivatives where it is C2′-endo. All of the studied derivatives exhibited mild-to-moderate anti-inflammatory activity (~15.64–20.63% inhibition) at 40 mg kg−1 dose and LD50 values > 400 mg kg−1 in albino rats.


2016 ◽  
Vol 40 ◽  
pp. 69-79 ◽  
Author(s):  
Derek Thomson ◽  
Charalampos G. Panagos ◽  
Radhakrishnan Venkatasamy ◽  
Claire Moss ◽  
Joanne Robinson ◽  
...  

Author(s):  
Marcia L.L. Silveira ◽  
Fhernanda R. Smiderle ◽  
Franciane Agostini ◽  
Eduardo M. Pereira ◽  
Mariane Bonatti-Chaves ◽  
...  

2018 ◽  
Vol 186 ◽  
pp. 91-99 ◽  
Author(s):  
Iglesias de Lacerda Bezerra ◽  
Adriana Rute Cordeiro Caillot ◽  
Lais Cristina Gusmão Ferreira Palhares ◽  
Arquimedes Paixão Santana-Filho ◽  
Suely Ferreira Chavante ◽  
...  

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